MIB1 - mindbomb homolog 1 (Drosophila)
Entrez Gene Name: mindbomb homolog 1 (Drosophila)
Entrez GeneID: Human(57534)
, Mouse(225164), Rat(307594)
, Mouse(225164), Rat(307594) Synonyms: DIP-1, DKFZp686I0769, DKFZp761M1710, E430019M12Rik, FLJ90676, MGC129659, MGC129660, MGC18948, MIB, MIB1, Mib1 predicted, mKIAA1323, ZZANK2, ZZZ6
Gene Summary
No Data Available
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
Biological Process
blood vessel development, heart development, heart looping, in utero embryonic development, modification-dependent protein catabolic process, negative regulation of neuron differentiation, neural tube formation, Notch signaling pathway, positive regulation of endocytosis, protein ubiquitination, somitogenesis
Literature References
- 17728463Choe EA, Liao L, Zhou JY, Cheng D, Duong DM, Jin P, Tsai LH, Peng J. Neuronal morphogenesis is regulated by the interplay between cyclin-dependent kinase 5 and the ubiquitin ligase mind bomb 1.J Neurosci 2007 Aug 29;27(35):9503-12
- 16000382Koo BK, Lim HS, Song R, Yoon MJ, Yoon KJ, Moon JS, Kim YW, Kwon MC, Yoo KW, Kong MP, Lee J, Chitnis AB, Kim CH, Kong YY. Mind bomb 1 is essential for generating functional Notch ligands to activate Notch.Development 2005 08 1;132(15):3459-70
- 12351649Jin Y, Blue EK, Dixon S, Shao Z, Gallagher PJ. A DAPK interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes TNF-induced apoptosis and regulates the cellular levels of DAPK.J Biol Chem 2002 12 6;277(49):46980-6 View 136 categorized literature findings and their references in IPA
Molecular Functions
ligase activity, metal ion binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding
