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LAD1 - ladinin 1
Entrez Gene Name: ladinin 1
Synonyms: LAD1, LadA, LADININ 1, MGC10355

Gene Summary

  • Human (3898): The protein encoded by this gene may be an anchoring filament that is a component of basement membranes. It may contribute to the stability of the association of the epithelial layers with the underlying mesenchyme. [provided by RefSeq]

Cell Regulation

Regulates:
  • No Data Available
Regulated by:
  • HNF4A
  • sulindac
  • methylprednisolone
View all 8 in IPA
Role in cell:
  • No Data Available
Disease:
  • lymphoid cancer
  • angioimmunoblastic t-cell lymphoma
View all 4 in IPA

Biological Process

No Data Available

Cellular Components

basement membrane, extracellular region, extracellular space, proteinaceous extracellular matrix

Literature References

  • 14595018Chabardès-Garonne D, Mejéan A, Aude JC, Cheval L, Di Stefano A, Gaillard MC, Imbert-Teboul M, Wittner M, Balian C, Anthouard V, Robert C, Ségurens B, Wincker P, Weissenbach J, Doucet A, Elalouf JM. A panoramic view of gene expression in the human kidney.Proc Natl Acad Sci U S A 2003 Nov 11;100(23):13710-5
  • 14988562Odom DT, Zizlsperger N, Gordon DB, Bell GW, Rinaldi NJ, Murray HL, Volkert TL, Schreiber J, Rolfe PA, Gifford DK, Fraenkel E, Bell GI, Young RA. Control of pancreas and liver gene expression by HNF transcription factors.Science 2004 02 27;303(5662):1378-81
  • 14617768Rogatsky I, Wang JC, Derynck MK, Nonaka DF, Khodabakhsh DB, Haqq CM, Darimont BD, Garabedian MJ, Yamamoto KR. Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor.Proc Natl Acad Sci U S A 2003 Nov 25;100(24):13845-50
  • View 32 categorized literature findings and their references in IPA

Molecular Functions

structural molecule activity

Pathways

No Data Available

Protein Domains

structural molecule

Subcellular Locations

extracellular matrix, extracellular space

IPA Extras

View additional information available in IPA's curated and annotated database: