CHRNA2 - cholinergic receptor, nicotinic, alpha 2 (neuronal)
Entrez Gene Name: cholinergic receptor, nicotinic, alpha 2 (neuronal)
Entrez GeneID: Human(1135)
, Mouse(110902), Rat(170945)
, Mouse(110902), Rat(170945) Synonyms: ACHR, Acra-2, BC011490, CHRNA2, MGC18795, nAChR alpha2
Gene Summary
- Rat (170945): agonist-binding subunit of neuronal nicotinic acetylcholine receptor [RGD]
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
Cellular Components
cell junction, integral to membrane, membrane, membrane fraction, nicotinic acetylcholine-gated receptor-channel complex, plasma membrane, postsynaptic membrane, synapse
Literature References
- 15016836Xiao Y, Kellar KJ. The comparative pharmacology and up-regulation of rat neuronal nicotinic receptor subtype binding sites stably expressed in transfected Mammalian cells.J Pharmacol Exp Ther 2004 Jul 01;310(1):98-107
- 15213299Moretti M, Vailati S, Zoli M, Lippi G, Riganti L, Longhi R, Viegi A, Clementi F, Gotti C. Nicotinic Acetylcholine Receptor Subtypes Expression during Rat Retina Development and Their Regulation by Visual Experience.Mol Pharmacol 2004 Jul 01;66(1):85-96
- 15155845Salminen O, Murphy KL, McIntosh JM, Drago J, Marks MJ, Collins AC, Grady SR. Subunit composition and pharmacology of two classes of striatal presynaptic nicotinic acetylcholine receptors mediating dopamine release in mice.Mol Pharmacol 2004 Jun 01;65(6):1526-35 View 341 categorized literature findings and their references in IPA
Molecular Functions
acetylcholine binding, acetylcholine receptor activity, drug binding, extracellular ligand-gated ion channel activity, ion channel activity, neurotransmitter receptor activity, nicotinic acetylcholine-activated cation-selective channel activity, receptor activity
Protein Domains
acetylcholine receptor, extracellular ligand binding domain, extracellular ligand-gated ion channel, GABA-A receptor, ion channel, neurotransmitter-gated ion channel ligand binding domain, nicotinic acetylcholine-activated cation-selective channel, transmembrane receptor
