CSNK1A1 - casein kinase 1, alpha 1
Entrez Gene Name: casein kinase 1, alpha 1
Entrez GeneID: Human(1452)
, Mouse(93687), Rat(113927)
, Mouse(93687), Rat(113927) Synonyms: 2610208K14Rik, 4632404G05Rik, 5430427P18RIK, CASEIN KINASE 1 ALPHA, CK1, CK1 ALPHA, CKI ALPHA, Csnk1a, CSNK1A1, HLCDGP1, MGC156603, MGC29354, MGC30571, PRO2975
Gene Summary
- Rat (113927): splice variant isoforms CKI alpha and CKI alpha L both have casein kinase I activity but display differences in substrate kinetics [RGD]
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
Disease:
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Biological Process
cell morphogenesis, protein amino acid phosphorylation, Wnt receptor signaling pathway
Literature References
- 19118383Bidère N, Ngo VN, Lee J, Collins C, Zheng L, Wan F, Davis RE, Lenz G, Anderson DE, Arnoult D, Vazquez A, Sakai K, Zhang J, Meng Z, Veenstra TD, Staudt LM, Lenardo MJ. Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival.Nature 2009 Mar 05;458(7234):92-6
- 15502875John B, Enright AJ, Aravin A, Tuschl T, Sander C, Marks DS. Human MicroRNA targets.PLoS Biol 2004 11 1;2(11):e363
- 9630228Zhu J, Shibasaki F, Price R, Guillemot JC, Yano T, Dotsch V, Wagner G, Ferrara P, McKeon F. Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1.Cell 1998 05 29;93(5):851-61 View 395 categorized literature findings and their references in IPA
Molecular Functions
ATP binding, glycoprotein binding, kinase activity, magnesium ion binding, nucleotide binding, peptide binding, phosphoprotein binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, transferase activity
Protein Domains
Alcohol group acceptor phosphotransferase, ATP binding, kinase, magnesium ion binding, peptide binding, protein binding, protein serine/threonine kinase
