DPYSL2 - dihydropyrimidinase-like 2
Entrez Gene Name: dihydropyrimidinase-like 2
Entrez GeneID: Human(1808)
, Mouse(12934), Rat(25416)
, Mouse(12934), Rat(25416) Synonyms: AI851130, CRMP2, DHPRP2, DPYSL2, DRP-2, Musunc33, TOAD-64, Tuc-2a, Ulip2
Gene Summary
- Rat (25416): membrane-associated protein, may be important for axonal outgrowth and pathfinding [RGD]
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
Biological Process
cell differentiation, multicellular organismal development, nervous system development, nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, regulation of axon extension, signal transduction
Literature References
- 15652488Yoshimura T, Kawano Y, Arimura N, Kawabata S, Kikuchi A, Kaibuchi K. GSK-3beta Regulates Phosphorylation of CRMP-2 and Neuronal Polarity.Cell 2005 Jan 14;120(1):137-49
- 15630019Govek EE, Newey SE, Van Aelst L. The role of the Rho GTPases in neuronal development.Genes Dev 2005 01 1;19(1):1-49
- 18460467Cole AR, Soutar MP, Rembutsu M, van Aalten L, Hastie CJ, McLauchlan H, Peggie M, Balastik M, Lu KP, Sutherland C. Relative resistance of Cdk5-phosphorylated CRMP2 to dephosphorylation.J Biol Chem 2008 Jun 27;283(26):18227-37 View 395 categorized literature findings and their references in IPA
Molecular Functions
dihydropyrimidinase activity, hydrolase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, protein binding
Subcellular Locations
axons, cell body, cellular membrane, cytoplasm, cytosol, dendrites, detergent-insoluble fractions, detergent-soluble fraction, growth cone, membrane fraction, membrane processes, microtubule tips, microtubules, midbody, mitotic spindle, myelin enriched fraction, neurites, nucleus, soluble fraction
