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TNF - tumor necrosis factor (TNF superfamily, member 2)

Antibodies
Species Filter: Reset | human | mouse | rat
Product #
Species
Description
T8300 human Anti-Tumor Necrosis Factor-α antibody produced in rabbit 2 mg/mL, IgG fraction of antiserum, buffered aqueous solution
F6651 human Monoclonal Anti-Tumor Necrosis Factor-α–Fluorescein antibody produced in mouse clone 6402.31, purified immunoglobulin, buffered aqueous solution
T2315 human Anti-Tumor Necrosis Factor Soluble Receptor Type II antibody produced in goat IgG fraction of antiserum, lyophilized powder
GW10844F human Anti-Tumor Necrosis Factor-α antibody produced in chicken affinity isolated antibody, buffered aqueous solution
WH0007124M2 human Monoclonal Anti-TNF antibody produced in mouse clone 1C3-A1-F4, purified immunoglobulin, buffered aqueous solution
T1815 human Monoclonal Anti-Tumor Necrosis Factor Receptor II antibody produced in mouse clone 22221.311, purified immunoglobulin, lyophilized powder
T6817 human Monoclonal Anti-Tumor Necrosis Factor-α antibody produced in mouse clone 28401.111, purified immunoglobulin, lyophilized powder
T0813 human Anti-Tumor Necrosis Factor-α antibody produced in goat affinity isolated antibody, lyophilized powder
T2440 mouse Anti-Tumor Necrosis Factor Soluble Receptor II antibody produced in goat affinity isolated antibody, lyophilized powder
T0938 mouse Anti-Tumor Necrosis Factor-α antibody produced in goat affinity isolated antibody, lyophilized powder
T3198 rat Monoclonal Anti-Tumor Necrosis Factor-α antibody produced in mouse clone 45418.111, purified immunoglobulin, lyophilized powder
T2824 rat, mouse Monoclonal Anti-Tumor Necrosis Factor-α antibody produced in hamster ~2 mg/mL, clone TN3-19.12, purified immunoglobulin, buffered aqueous solution

Small Molecule - Antagonist
Species Filter: Reset | human | mouse | rat
Product #
Species
Description
00010 human Abietic acid technical, ~75% (GC)
A9424 human Abietic acid ≥65% (GC)
F3917 human Forskolin from Coleus forskohlii, for molecular biology, ≥98%
119792 human Podocarpic acid 98%
F6886 human Forskolin from Coleus forskohlii, ≥98% (HPLC), powder
P9672 human Probucol
S0193 human, rat SKF-86002 ≥98% (HPLC), solid
F505 human, rat, mouse Fisetin
46340 human, rat, mouse Fisetin BioChemika, ≥99.0% (HPLC)
F4043 human, rat, mouse Fisetin
70050 human, rat, mouse Myricetin BioChemika, ≥96.0% (HPLC)
M6760 human, rat, mouse Myricetin ≥96.0%, crystalline
T150 human, rat, mouse (−)-Thalidomide >98%, solid
T151 human, rat, mouse (+)-Thalidomide solid
10798 human, rat, mouse Apigenin BioChemika, ≥95.0% (HPLC)
A3145 human, rat, mouse Apigenin ~95% (TLC), from parsley, powder
L9283 human, rat, mouse Luteolin ≥98% (TLC), powder
62696 human, rat, mouse Luteolin BioChemika, ≥99.0% (TLC)

Small Molecule - Blocker
Product #
Species
Description
T9177 human Tyrphostin AG 126 ≥90%

Small Molecule - Inhibitor
Species Filter: Reset | human | mouse | rat
Product #
Species
Description
S8307 human SB 203580 solid
P1784 human, rat Pentoxifylline solid
T144 human, rat, mouse (±)-Thalidomide >98%, solid
D4902 human, rat, mouse Dexamethasone powder, ≥97%, cell culture tested
31375 human, rat, mouse Dexamethasone Ph Eur
34166 human, rat, mouse Betamethasone VETRANAL®, analytical standard, free compound
D9184 human, rat, mouse Dexamethasone meets USP testing specifications
D6645 human, rat, mouse Dexamethasone Sigma Reference Standard
D1756 human, rat, mouse Dexamethasone ≥98% (HPLC), powder
46165 human, rat, mouse Dexamethasone VETRANAL®, analytical standard
B9675 human, rat, mouse Betamethasone meets USP testing specifications
A7410 human, rat, mouse Amiloride hydrochloride hydrate ≥98% (TLC), powder
D8893 human, rat, mouse Dexamethasone powder, γ-irradiated, cell culture tested
B7005 human, rat, mouse Betamethasone ≥98%

shRNA
Species Filter: Reset | Human | Mouse
Type
Species
Description
SHCLNG-NM_013693 Mouse MISSION® shRNA Bacterial Glycerol Stock
SHCLNG-NM_000594 Human MISSION® shRNA Bacterial Glycerol Stock
SHCLND-NM_013693 Mouse MISSION® shRNA Plasmid DNA
SHCLND-NM_000594 Human MISSION® shRNA Plasmid DNA
SHCLNV-NM_013693 Mouse MISSION® shRNA Lentiviral Transduction Particles
SHCLNV-NM_000594 Human MISSION® shRNA Lentiviral Transduction Particles

shRNA Panels
Product #
Species
Description
SH2221 human MISSION® shRNA Human Gene Family Set, DNA Cell Adhesion Genes
SH0831 human MISSION® shRNA Human Gene Family Set, Lentiviral Particles Cytokines and Chemokines
SH2231 human MISSION® shRNA Human Gene Family Set, Lentiviral Particles Cell Adhesion Genes
SH2821 human MISSION® shRNA Human Gene Family Set, DNA T-Cell Activation
SH2421 human MISSION® shRNA Human Gene Family Set, DNA p53 Pathway
SH2811 human MISSION® shRNA Human Gene Family Set, Bacterial Glycerol Stock T-Cell Activation
SH0821 human MISSION® shRNA Human Gene Family Set, DNA Cytokines and Chemokines
SH2831 human MISSION® shRNA Human Gene Family Set, Lentiviral Particles T-Cell Activation
SH2411 human MISSION® shRNA Human Gene Family Set, Bacterial Glycerol Stock p53 Pathway
SH0811 human MISSION® shRNA Human Gene Family Set, Bacterial Glycerol Stock Cytokines and Chemokines
SH2431 human MISSION® shRNA Human Gene Family Set, Lentiviral Particles p53 Pathway
SH1921 human MISSION® shRNA Human Gene Family Set, DNA Apoptosis Pathway
SH1931 human MISSION® shRNA Human Gene Family Set, Lentiviral Particles Apoptosis Pathway
SH1911 human MISSION® shRNA Human Gene Family Set, Bacterial Glycerol Stock Apoptosis Pathway
SH2211 human MISSION® shRNA Human Gene Family Set, Bacterial Glycerol Stock Cell Adhesion Genes

siRNA Panels
Product #
Species
Description
SI00100 human MISSION® siRNA Human Druggable Genome Library 6650 targets
SI04100 human MISSION® siRNA Human Gene Family Panels Human Growth Factors/Receptors Panel, 375 targets

Antibody Arrays
Species Filter: Reset | human | mouse | rat
Product #
Species
Description
XP725 human, rat, mouse Panorama® Antibody Microarray - XPRESS Profiler725 Kit

CompoZr ZFN
Product #
Description
CSTZFN-1KT CompoZr™ Zinc Finger Nuclease Technology

 
siRNA

siRNA ID
Species
RefSeq ID
Approx. siRNA Start
siRNA Type
Ranking
SASI_Hs01_00011378 HUMAN NM_000594 1018 MISSION® siRNA 1
SASI_Hs01_00011379 HUMAN NM_000594 728 MISSION® siRNA 2
SASI_Hs01_00011380 HUMAN NM_000594 421 MISSION® siRNA 3
SASI_Hs01_00011381 HUMAN NM_000594 1065 MISSION® siRNA 4
SASI_Hs01_00011382 HUMAN NM_000594 839 MISSION® siRNA 5
SASI_Hs01_00011383 HUMAN NM_000594 733 MISSION® siRNA 6
SASI_Hs01_00011384 HUMAN NM_000594 839 MISSION® siRNA 7
SASI_Hs01_00011385 HUMAN NM_000594 826 MISSION® siRNA 8
SASI_Hs01_00011386 HUMAN NM_000594 1040 MISSION® siRNA 9
SASI_Hs01_00011387 HUMAN NM_000594 392 MISSION® siRNA 10
SASI_Rn01_00033334 RAT NM_012675 495 MISSION® siRNA 1
SASI_Rn01_00033336 RAT NM_012675 813 MISSION® siRNA 2
SASI_Rn01_00033337 RAT NM_012675 984 MISSION® siRNA 3
SASI_Rn01_00033338 RAT NM_012675 617 MISSION® siRNA 4
SASI_Rn01_00033339 RAT NM_012675 855 MISSION® siRNA 5
SASI_Rn01_00033341 RAT NM_012675 378 MISSION® siRNA 6
SASI_Rn01_00033342 RAT NM_012675 336 MISSION® siRNA 7
SASI_Rn01_00033343 RAT NM_012675 515 MISSION® siRNA 8
SASI_Rn02_00259959 RAT NM_012675 783 MISSION® siRNA 9
SASI_Rn02_00259960 RAT NM_012675 496 MISSION® siRNA 10
SASI_Rn01_00033335 RAT NM_012675 283 MISSION® siRNA 11
SASI_Rn01_00033340 RAT NM_012675 235 MISSION® siRNA 12
SASI_Mm01_00047023 MOUSE NM_013693 862 MISSION® siRNA 1
SASI_Mm01_00047024 MOUSE NM_013693 829 MISSION® siRNA 2
SASI_Mm02_00322582 MOUSE NM_013693 980 MISSION® siRNA 3
SASI_Mm01_00047027 MOUSE NM_013693 794 MISSION® siRNA 4
SASI_Mm01_00047028 MOUSE NM_013693 867 MISSION® siRNA 5
SASI_Mm01_00047029 MOUSE NM_013693 722 MISSION® siRNA 6
SASI_Mm01_00047030 MOUSE NM_013693 391 MISSION® siRNA 7
SASI_Mm01_00047031 MOUSE NM_013693 771 MISSION® siRNA 8
SASI_Mm01_00047032 MOUSE NM_013693 343 MISSION® siRNA 9
SASI_Mm02_00322583 MOUSE NM_013693 739 MISSION® siRNA 10
SASI_Mm01_00047025 MOUSE NM_013693 868 MISSION® siRNA 11
SASI_Mm01_00047026 MOUSE NM_013693 992 MISSION® siRNA 12
Sigma's MISSION® siRNA 
have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. Critical rules incorporated into the best-in-class Rosetta siRNA design algorithm lead to siRNA of increased target specificity and knockdown for low abundance messages.