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ADRA1A - adrenergic, alpha-1A-, receptor

Antibodies
Species Filter: Reset | human | mouse | rat
Product #
Species
Description
A4604 human Anti-α1C Adrenergic Receptor antibody produced in rabbit affinity isolated antibody, buffered aqueous solution
WH0000148M1 human Monoclonal Anti-ADRA1A antibody produced in mouse clone 4C7, purified immunoglobulin, buffered aqueous solution
A270 human, rat, mouse Anti-α1 Adrenergic Receptor antibody produced in rabbit affinity isolated antibody, buffered aqueous solution

Small Molecule - Agonist
Product #
Species
Description
X6000 human Xylometazoline hydrochloride
C223 human Cirazoline hydrochloride solid
A0937 human (±)-Norepinephrine (+)-bitartrate salt
D155 human Dihydroergocristine methanesulfonate salt
T4264 human Tetrahydrozoline hydrochloride ≥98%
S0752 human (±)-Synephrine ≥98%
N5504 human Naphazoline hydrochloride
F6800 human Fenoldopam monohydrobromide ≥98%
E4642 human (±)-Epinephrine hydrochloride
O0250 human (±)-Octopamine hydrochloride ≥95%, solid
E4375 human (−)-Epinephrine (+)-bitartrate salt solid
P6126 human (R)-(−)-Phenylephrine hydrochloride powder
M6524 human Methoxamine hydrochloride

Small Molecule - Antagonist
Species Filter: Reset | human | mouse | rat
Product #
Species
Description
B019 human Phenoxybenzamine hydrochloride ≥97%, powder
P7561 human Phentolamine methanesulfonate salt ≥98% (TLC), powder
M5154 human Moxisylyte hydrochloride >99% (TLC), powder
D4526 human Doxepin hydrochloride ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder
U104 human UK 14,304
F4303 human Fiduxosin hydrochloride >98% (HPLC), solid
N158 human Naftopidil hydrochloride hydrate solid
T4680 human Terazosin hydrochloride ≥98% (TLC), powder
U100 human Urapidil hydrochloride solid
F6145 human Fenspiride hydrochloride >99% (TLC), powder
P7791 human Prazosin hydrochloride ≥99% (TLC)
V4629 human (±)-Verapamil hydrochloride ≥99.0% (titration), powder
U101 human 5-Methylurapidil solid
P6402 human Perphenazine
E3263 human Efaroxan hydrochloride ≥98% (HPLC)
B016 human Benoxathian hydrochloride solid
T1395 human, rat (±)-α-Lipoic acid cell culture tested, ≥99%
S0693 human, rat SB 204741 >98% (HPLC)
D9815 human, rat Doxazosin mesylate ≥97% (HPLC), powder
E2031 human, rat Eliprodil ≥98% (HPLC), solid
A7257 human, rat (−)-Norepinephrine ≥98%, crystalline
C6305 human, rat Clozapine
D5290 human, rat (−)-3,4-Dihydroxynorephedrine ≥90%
H1512 human, rat Haloperidol powder
34002 human, rat (S)-(−)-Sulpiride VETRANAL®, analytical standard
594687 human, rat α-Sexithiophene
B9308 human, rat BP897 >98% (HPLC), solid
L3040 human, rat L-765,314 hydrate ≥98% (HPLC), solid
62320 human, rat (±)-α-Lipoic acid ≥98.0%
T5625 human, rat (±)-α-Lipoic acid synthetic, ≥99% (titration), powder
S7771 human, rat (S)-(−)-Sulpiride ≥98% (HPLC)
R103 human, rat Ritanserin solid
B012 human, rat 6-Fluoronorepinephrine hydrochloride solid
S0568 human, rat SB-200646 hydrochloride >98% (HPLC), solid
C7230 human, rat N-[2-(4-(4-Chlorophenyl)piperazin-1-yl)ethyl]-3-methoxybenzamide solid
51330 human, rat Harmaline purum
S7395 human, rat Spiperone solid
M0443 human, rat, mouse Mirtazapine ≥98% (HPLC), solid
547905 human, rat, mouse 2,2′:5′,2′′:5′′,2′′′-Quaterthiophene 96%
E1635 rat (±)-Epinephrine ≥95%
282553 rat (1R,2S)-(−)-Norephedrine 99%
74530 rat L-(−)-Norephedrine purum, ≥98.0% (NT)
E4250 rat (−)-Epinephrine
02252 rat (−)-Epinephrine USP
M22601 rat, mouse 1-(2-Methoxyphenyl)piperazine 98%
65225 rat, mouse 1-(2-Methoxyphenyl)piperazine purum, ≥97.0% (NT)

Small Molecule - Inhibitor
Product #
Species
Description
N7889 human Nicergoline ~97% (TLC)

shRNA
Species Filter: Reset | Human | Mouse
Type
Species
Description
SHCLNG-NM_013461 Mouse MISSION® shRNA Bacterial Glycerol Stock
SHCLNG-NM_033303 Human MISSION® shRNA Bacterial Glycerol Stock
SHCLND-NM_013461 Mouse MISSION® shRNA Plasmid DNA
SHCLND-NM_033303 Human MISSION® shRNA Plasmid DNA
SHCLNV-NM_013461 Mouse MISSION® shRNA Lentiviral Transduction Particles
SHCLNV-NM_033303 Human MISSION® shRNA Lentiviral Transduction Particles

shRNA Panels
Product #
Species
Description
SH0231 human MISSION® shRNA Human Gene Family Set, Lentiviral Particles G-Protein Coupled Receptors
SH0221 human MISSION® shRNA Human Gene Family Set, DNA G-Protein Coupled Receptors
SH0211 human MISSION® shRNA Human Gene Family Set, Bacterial Glycerol Stock G-Protein Coupled Receptors

siRNA Panels
Product #
Species
Description
SI00100 human MISSION® siRNA Human Druggable Genome Library 6650 targets
SI08100 human MISSION® siRNA Human Gene Family Panels GPCR Panel, 304 targets

CompoZr ZFN
Product #
Description
CSTZFN-1KT CompoZr™ Zinc Finger Nuclease Technology

 
siRNA

siRNA ID
Species
RefSeq ID
Approx. siRNA Start
siRNA Type
Ranking
SASI_Hs02_00303073 HUMAN NM_000680 436 MISSION® siRNA 1
SASI_Hs02_00303074 HUMAN NM_000680 1319 MISSION® siRNA 2
SASI_Hs02_00303075 HUMAN NM_000680 1411 MISSION® siRNA 3
SASI_Hs01_00047401 HUMAN NM_000680 802 MISSION® siRNA 4
SASI_Hs01_00047402 HUMAN NM_000680 575 MISSION® siRNA 5
SASI_Hs01_00047404 HUMAN NM_000680 609 MISSION® siRNA 6
SASI_Hs02_00303076 HUMAN NM_000680 1077 MISSION® siRNA 7
SASI_Hs02_00303077 HUMAN NM_000680 1441 MISSION® siRNA 8
SASI_Hs01_00047405 HUMAN NM_000680 570 MISSION® siRNA 9
SASI_Hs02_00303078 HUMAN NM_000680 765 MISSION® siRNA 10
SASI_Hs01_00047400 HUMAN NM_000680 1210 MISSION® siRNA 11
SASI_Hs01_00047403 HUMAN NM_000680 952 MISSION® siRNA 12
SASI_Hs01_00047406 HUMAN NM_000680 1195 MISSION® siRNA 13
SASI_Hs01_00047407 HUMAN NM_000680 1111 MISSION® siRNA 14
SASI_Hs01_00047408 HUMAN NM_000680 1190 MISSION® siRNA 15
SASI_Hs01_00047409 HUMAN NM_000680 1112 MISSION® siRNA 16
SASI_Mm01_00194699 MOUSE NM_013461 1675 MISSION® siRNA 1
SASI_Mm01_00194700 MOUSE NM_013461 1884 MISSION® siRNA 2
SASI_Mm01_00194701 MOUSE NM_013461 990 MISSION® siRNA 3
SASI_Mm01_00194702 MOUSE NM_013461 1298 MISSION® siRNA 4
SASI_Mm01_00194703 MOUSE NM_013461 2153 MISSION® siRNA 5
SASI_Mm01_00194704 MOUSE NM_013461 1242 MISSION® siRNA 6
SASI_Mm01_00194705 MOUSE NM_013461 1107 MISSION® siRNA 7
SASI_Mm01_00194706 MOUSE NM_013461 2322 MISSION® siRNA 8
SASI_Mm01_00194707 MOUSE NM_013461 2270 MISSION® siRNA 9
SASI_Mm02_00322068 MOUSE NM_013461 1748 MISSION® siRNA 10
SASI_Mm01_00194708 MOUSE NM_013461 2283 MISSION® siRNA 11
SASI_Rn02_00261538 RAT NM_017191 1106 MISSION® siRNA 1
SASI_Rn02_00261539 RAT NM_017191 671 MISSION® siRNA 2
SASI_Rn01_00108036 RAT NM_017191 970 MISSION® siRNA 3
SASI_Rn01_00108038 RAT NM_017191 1175 MISSION® siRNA 4
SASI_Rn02_00261540 RAT NM_017191 1030 MISSION® siRNA 5
SASI_Rn02_00261541 RAT NM_017191 530 MISSION® siRNA 6
SASI_Rn01_00108040 RAT NM_017191 376 MISSION® siRNA 7
SASI_Rn01_00108041 RAT NM_017191 761 MISSION® siRNA 8
SASI_Rn01_00108042 RAT NM_017191 324 MISSION® siRNA 9
SASI_Rn02_00261542 RAT NM_017191 368 MISSION® siRNA 10
SASI_Rn01_00108035 RAT NM_017191 1264 MISSION® siRNA 11
SASI_Rn01_00108037 RAT NM_017191 1466 MISSION® siRNA 12
SASI_Rn01_00108039 RAT NM_017191 648 MISSION® siRNA 13
SASI_Rn01_00108043 RAT NM_017191 921 MISSION® siRNA 14
SASI_Rn01_00108044 RAT NM_017191 1372 MISSION® siRNA 15
SASI_Hs02_00361121 HUMAN NM_033302 436 MISSION® siRNA 1
SASI_Hs02_00361122 HUMAN NM_033302 1310 MISSION® siRNA 2
SASI_Hs02_00361123 HUMAN NM_033302 1410 MISSION® siRNA 3
SASI_Hs01_00178896 HUMAN NM_033302 805 MISSION® siRNA 4
SASI_Hs01_00178897 HUMAN NM_033302 580 MISSION® siRNA 5
SASI_Hs01_00178899 HUMAN NM_033302 617 MISSION® siRNA 6
SASI_Hs02_00361124 HUMAN NM_033302 1082 MISSION® siRNA 7
SASI_Hs02_00361125 HUMAN NM_033302 1439 MISSION® siRNA 8
SASI_Hs01_00178900 HUMAN NM_033302 571 MISSION® siRNA 9
SASI_Hs02_00361126 HUMAN NM_033302 769 MISSION® siRNA 10
SASI_Hs01_00178895 HUMAN NM_033302 1206 MISSION® siRNA 11
SASI_Hs01_00178898 HUMAN NM_033302 949 MISSION® siRNA 12
SASI_Hs01_00178901 HUMAN NM_033302 1191 MISSION® siRNA 13
SASI_Hs01_00178902 HUMAN NM_033302 1112 MISSION® siRNA 14
SASI_Hs01_00178903 HUMAN NM_033302 1186 MISSION® siRNA 15
SASI_Hs01_00178904 HUMAN NM_033302 1109 MISSION® siRNA 16
SASI_Hs02_00361127 HUMAN NM_033303 436 MISSION® siRNA 1
SASI_Hs02_00361128 HUMAN NM_033303 1316 MISSION® siRNA 2
SASI_Hs02_00361129 HUMAN NM_033303 1406 MISSION® siRNA 3
SASI_Hs01_00068700 HUMAN NM_033303 800 MISSION® siRNA 4
SASI_Hs01_00068701 HUMAN NM_033303 582 MISSION® siRNA 5
SASI_Hs01_00068703 HUMAN NM_033303 617 MISSION® siRNA 6
SASI_Hs02_00361130 HUMAN NM_033303 1078 MISSION® siRNA 7
SASI_Hs02_00361131 HUMAN NM_033303 1436 MISSION® siRNA 8
SASI_Hs01_00068704 HUMAN NM_033303 573 MISSION® siRNA 9
SASI_Hs02_00361132 HUMAN NM_033303 773 MISSION® siRNA 10
SASI_Hs01_00068699 HUMAN NM_033303 1207 MISSION® siRNA 11
SASI_Hs01_00068702 HUMAN NM_033303 952 MISSION® siRNA 12
SASI_Hs01_00068705 HUMAN NM_033303 1196 MISSION® siRNA 13
SASI_Hs01_00068706 HUMAN NM_033303 1111 MISSION® siRNA 14
SASI_Hs01_00068707 HUMAN NM_033303 1193 MISSION® siRNA 15
SASI_Hs01_00068708 HUMAN NM_033303 1112 MISSION® siRNA 16
SASI_Hs02_00361133 HUMAN NM_033304 435 MISSION® siRNA 1
SASI_Hs02_00361134 HUMAN NM_033304 1317 MISSION® siRNA 2
SASI_Hs02_00361135 HUMAN NM_033304 1415 MISSION® siRNA 3
SASI_Hs01_00099642 HUMAN NM_033304 798 MISSION® siRNA 4
SASI_Hs01_00099643 HUMAN NM_033304 574 MISSION® siRNA 5
SASI_Hs01_00099645 HUMAN NM_033304 613 MISSION® siRNA 6
SASI_Hs02_00361136 HUMAN NM_033304 1085 MISSION® siRNA 7
SASI_Hs02_00361137 HUMAN NM_033304 1441 MISSION® siRNA 8
SASI_Hs01_00099646 HUMAN NM_033304 566 MISSION® siRNA 9
SASI_Hs02_00361138 HUMAN NM_033304 769 MISSION® siRNA 10
SASI_Hs01_00099641 HUMAN NM_033304 972 MISSION® siRNA 11
SASI_Hs01_00099644 HUMAN NM_033304 714 MISSION® siRNA 12
SASI_Hs01_00099647 HUMAN NM_033304 955 MISSION® siRNA 13
SASI_Hs01_00099648 HUMAN NM_033304 866 MISSION® siRNA 14
SASI_Hs01_00099649 HUMAN NM_033304 950 MISSION® siRNA 15
SASI_Hs01_00099650 HUMAN NM_033304 874 MISSION® siRNA 16
Sigma's MISSION® siRNA 
have been designed using a world-class siRNA design algorithm licensed from Rosetta Inpharmatics, a leader in advanced siRNA research. Critical rules incorporated into the best-in-class Rosetta siRNA design algorithm lead to siRNA of increased target specificity and knockdown for low abundance messages.