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TSPAN13 - tetraspanin 13
Canonical
Pathway
Entrez Gene Name: tetraspanin 13
Entrez GeneID: Human(27075)
, Mouse(66109), Rat(366602)
, Mouse(66109), Rat(366602) Synonyms: 1100001I23Rik, FLJ22934, MGC109170, NET-6, TM4SF13, TRANSMEMBRANE4, TSPAN13
Gene Summary
- Human (27075): The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
Regulates:
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Literature References
- 17965585Iwai K, Ishii M, Ohshima S, Miyatake K, Saeki Y. Expression and function of transmembrane-4 superfamily (tetraspanin) proteins in osteoclasts: reciprocal roles of Tspan-5 and NET-6 during osteoclastogenesis.Allergol Int 2007 Dec 01;56(4):457-63
- 15289333Hoek K, Rimm DL, Williams KR, Zhao H, Ariyan S, Lin A, Kluger HM, Berger AJ, Cheng E, Trombetta ES, Wu T, Niinobe M, Yoshikawa K, Hannigan GE, Halaban R. Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas.Cancer Res 2004 Aug 01;64(15):5270-82
- 20711500Dyer MD, Neff C, Dufford M, Rivera CG, Shattuck D, Bassaganya-Riera J, Murali TM, Sobral BW. The Human-Bacterial Pathogen Protein Interaction Networks of Bacillus anthracis, Francisella tularensis, and Yersinia pestis.PLoS One 2010 Aug 09;5(8):e12089