HIST1H3F - histone cluster 1, H3f
Entrez Gene Name: histone cluster 1, H3f
Entrez GeneID: Human(8968)
, Mouse(319149)
, Mouse(319149) Synonyms: H3-143, H3-53, H3-b, H3-f, H3.2-221, H3/i, H3FI, Hist1, Hist1h3b, Hist1h3c, Hist1h3d, Hist1h3e, HIST1H3F, Histone 3.2
Gene Summary
- Human (8968): Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq]
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
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Literature References
- 17353931Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D. Large-scale mapping of human protein-protein interactions by mass spectrometry.Mol Syst Biol 2007 01 1;3:89
- 15647281Testa A, Donati G, Yan P, Romani F, Huang TH, Viganò MA, Mantovani R. Chromatin Immunoprecipitation (ChIP) on Chip Experiments Uncover a Widespread Distribution of NF-Y Binding CCAAT Sites Outside of Core Promoters.J Biol Chem 2005 Apr 08;280(14):13606-15
- 14993289Citterio E, Papait R, Nicassio F, Vecchi M, Gomiero P, Mantovani R, Di Fiore PP, Bonapace IM. Np95 is a histone-binding protein endowed with ubiquitin ligase activity.Mol Cell Biol 2004 Mar 01;24(6):2526-35
