YFG Logo
SPIC - Spi-C transcription factor (Spi-1/PU.1 related)

Entrez Gene Name: Spi-C transcription factor (Spi-1/PU.1 related)
Entrez GeneID: Human(121599), Mouse(20728), Rat(314711)
Synonyms: AU019198, C76795, MGC40611, Prf, SPIC

Gene Summary

No Data Available
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras

Cell Regulation

Regulates:
  • IL2RA
  • KIT
View all 4 in IPA
Regulated by:
  • No Data Available
Binds:
  • SP6
View all 2 in IPA
Role in cell:
  • No Data Available
Disease:
  • No Data Available

Biological Process

regulation of transcription, DNA-dependent, transcription

Cellular Components

nucleus

Literature References

  • 16887979Schweitzer BL, Huang KJ, Kamath MB, Emelyanov AV, Birshtein BK, Dekoter RP. Spi-C Has Opposing Effects to PU.1 on Gene Expression in Progenitor B Cells.J Immunol 2006 Aug 15;177(4):2195-207
  • 10187812Bemark M, Mårtensson A, Liberg D, Leanderson T. Spi-C, a novel Ets protein that is temporally regulated during B lymphocyte development.J Biol Chem 1999 Apr 9;274(15):10259-67
View 47 categorized literature findings and their references in IPA

Molecular Functions

DNA binding, sequence-specific DNA binding, transcription factor activity

Pathways

No Data Available

Protein Domains

DNA binding, ETS domain, transcription regulator

Subcellular Locations

nuclear fraction, nucleus

IPA Extras

View additional information available in IPA's curated and annotated database: