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SPIC - Spi-C transcription factor (Spi-1/PU.1 related)
Canonical
Pathway
Entrez Gene Name: Spi-C transcription factor (Spi-1/PU.1 related)
Entrez GeneID: Human(121599)
, Mouse(20728), Rat(314711)
, Mouse(20728), Rat(314711) Synonyms: AU019198, C76795, MGC40611, Prf, SPIC
Gene Summary
No Data Available
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
Role in cell:
|
Biological Process
blastocyst development, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent
Literature References
- 10187812Bemark M, Mårtensson A, Liberg D, Leanderson T. Spi-C, a novel Ets protein that is temporally regulated during B lymphocyte development.J Biol Chem 1999 Apr 9;274(15):10259-67
- 16887979Schweitzer BL, Huang KJ, Kamath MB, Emelyanov AV, Birshtein BK, Dekoter RP. Spi-C Has Opposing Effects to PU.1 on Gene Expression in Progenitor B Cells.J Immunol 2006 Aug 15;177(4):2195-207
- 19535594Wilkinson MB, Xiao G, Kumar A, LaPlant Q, Renthal W, Sikder D, Kodadek TJ, Nestler EJ. Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models.J Neurosci 2009 Jun 17;29(24):7820-32
Molecular Functions
DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity