HIST1H3D - histone cluster 1, H3d
Entrez Gene Name: histone cluster 1, H3d
Entrez GeneID: Human(8351)
, Mouse(382523), Rat(691496)
, Mouse(382523), Rat(691496) Synonyms: H3-b, H3/b, H3FB, HIST1H3D, LOC691496, OTTMUSG00000005773
Gene Summary
- Human (8351): Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq]
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
Regulates:
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Literature References
- 11799067Ren B, Cam H, Takahashi Y, Volkert T, Terragni J, Young RA, Dynlacht BD. E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints.Genes Dev 2002 Jan 15;16(2):245-56
- 17170127Raslova H, Kauffmann A, Sekkaï D, Ripoche H, Larbret F, Robert T, Le Roux DT, Kroemer G, Debili N, Dessen P, Lazar V, Vainchenker W. Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach.Blood 2007 Apr 15;109(8):3225-34 View 4 categorized literature findings and their references in IPA
