ACTG2 (includes EG:72) - actin, gamma 2, smooth muscle, enteric
Entrez Gene Name: actin, gamma 2, smooth muscle, enteric
Entrez GeneID: Human(72)
, Mouse(11475), Rat(25365)
, Mouse(11475), Rat(25365) Synonyms: 0610041G09Rik, a-SMA, ACT, Act-4, Acta2, ACTA3, ACTE, ACTG2 (includes EG:72), ACTGE, actin gamma, ACTL3, ACTSG, Actvs, Alpha smooth muscle actin, alpha-SMA, ENTERIC SMOOTH MUSCLE GAMMA ACTIN, MGC105507, SM Alpha Actin, SMalphaA, SMGA, SMOOTH MUSCLE GAMMA ACTIN, Vascular Smooth Muscle Alpha-Actin
Gene Summary
- Human (72): Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 2, encoded by this gene, is a smooth muscle actin found in enteric tissues. [provided by RefSeq]
- Rat (25365): may play a role in smooth muscle function [RGD]
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
Literature References
- 17218253Ayala R, Shu T, Tsai LH. Trekking across the brain: the journey of neuronal migration.Cell 2007 Jan 12;128(1):29-43
- 15630019Govek EE, Newey SE, Van Aelst L. The role of the Rho GTPases in neuronal development.Genes Dev 2005 01 1;19(1):1-49
- 14592989Stuven T, Hartmann E, Gorlich D. Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes.EMBO J 2003 11 3;22(21):5928-40 View 3281 categorized literature findings and their references in IPA
- Tight Junction Signaling
- Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes
- Actin Cytoskeleton Signaling
- Integrin Signaling
- Germ Cell-Sertoli Cell Junction Signaling
- VEGF Signaling
- Crosstalk between Dendritic Cells and Natural Killer Cells
- NRF2-mediated Oxidative Stress Response
- Leukocyte Extravasation Signaling
- ILK Signaling
- FAK Signaling
- Cellular Effects of Sildenafil (Viagra)
- Clathrin-mediated Endocytosis Signaling
- Mechanisms of Viral Exit from Host Cells
- Virus Entry via Endocytic Pathways
- Caveolar-mediated Endocytosis Signaling
- Agrin Interactions at Neuromuscular Junction
- Regulation of Actin-based Motility by Rho
