EMAIL THIS PAGE TO A FRIEND

Bioorganic & medicinal chemistry

Preparation and antitubercular activities of alkylated amino alcohols and their glycosylated derivatives.


PMID 17851083

Abstract

A series of N- and C-alkylated amino alcohols and of their protected galactopyranosyl derivatives was synthesized and evaluated for antitubercular activity. Five of these compounds displayed good activity, with a MIC below 12.5mug/mL. The presence of the carbohydrate slightly affected the antibacterial activity.