EMAIL THIS PAGE TO A FRIEND

Antimicrobial agents and chemotherapy

Pyrrolidine dithiocarbamate and diethyldithiocarbamate are active against growing and nongrowing persister Mycobacterium tuberculosis.


PMID 17876006

Abstract

Diethyldithiocarbamate (DETC) and pyrrolidine dithiocarbamate (PDTC) were highly active against tubercle bacilli, with MICs of 8 microg/ml and 0.13 microg/ml, respectively. DETC and PDTC were active against old cultures, enhanced pyrazinamide or pyrazinamide/rifampin activity, and had serum inhibitory titers of 1:2 and 1:4, respectively, in mice given 100 mg/kg orally.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

36650
DCC, puriss., ≥99.0% (GC)
C13H22N2