EMAIL THIS PAGE TO A FRIEND

Proceedings of the Japan Academy. Series B, Physical and biological sciences

Total synthesis and development of bioactive natural products.


PMID 18941289

Abstract

The first total synthesis and development of a variety of bioactive natural products have been accomplished by using carbohydrates as a chiral source. In addition, practically useful intermediates have been created, analogs of natural products have been prepared, their structure-activity relationships studied, and the large-scale preparations of medicinally useful compounds established. The key target molecules have been the "Big Four" antibiotics (macrolides, aminoglycosides, beta-lactams and tetracyclines), pyranonaphthoquinone antibiotics, glycosidase inhibitors, and a side-chain of cephem antibiotics.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

424218
3-Aminoisoxazole, 95%
C3H4N2O