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Antimicrobial agents and chemotherapy

Sitafloxacin activity against Helicobacter pylori isolates, including those with gyrA mutations.


PMID 19380599

Abstract

Sitafloxacin showed MICs of less than or equal to 0.5 microg/ml against 105 isolates of Helicobacter pylori, including 44 isolates with mutations in the gyrA gene. The highest MICs for garenoxacin and levofloxacin were 8 and 64 times, respectively, higher than the highest MICs observed for sitafloxacin.