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Chemical communications (Cambridge, England)

DNA-templated release of functional molecules with an azide-reduction-triggered immolative linker.


PMID 21369617

Abstract

Nucleic acid templated reactions have attracted significant attention for nucleic acid sensing. Herein we report a general design which extends the potential of nucleic acid templated reactions to unleash the function of a broad diversity of small molecules such as a transcription factor agonist, a cytotoxic or a fluorophore.

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