EMAIL THIS PAGE TO A FRIEND

Future medicinal chemistry

Bismuth compounds in medicinal chemistry.


PMID 22857536

Abstract

In recent years, the chemical potential of bismuth and bismuth compounds has been actively exploited. Bismuth salts are known for their low toxicity, making them potential valuable reagents for large-scale synthesis, which becomes more obvious when dealing with products such as active pharmaceutical ingredients or synthetic intermediates. Conversely, bismuth compounds have been widely used in medicine. After extensive use in the treatments of syphilis and other bacterial infections before the advent of modern antibiotics, bismuth compounds remain important for the treatment of several gastrointestinal disorders and also exhibit antimicrobial properties and cytotoxic activity, among others. This review updates relevant advances in the past few years, concerning the application of bismuth reagents and catalysts in innovative synthetic processes for the preparation of compounds of medicinal interest, as well as the preparation, biological evaluation and potential medicinal uses of bismuth compounds.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

GF86561354
Bismuth, foil, not light tested, 50x50mm, thickness 0.025mm, permanent polyester support, 99.97%
Bi
GF85045631
Bismuth, foil, not light tested, 50x50mm, thickness 0.01mm, permanent polyester support, 99.97%
Bi
GF80139438
Bismuth, foil, not light tested, 50x50mm, thickness 0.05mm, permanent polyester support, 99.97%
Bi
GF81875447
Bismuth, rod, 120mm, diameter 10.0mm, cast sticks, 100%
Bi
GF71052432
Bismuth, rod, 140mm, diameter 10.0mm, cast sticks, 100%
Bi
GF60966366
Bismuth, rod, 70mm, diameter 10.0mm, cast sticks, 100%
Bi
GF89918500
Bismuth, foil, 25x25mm, thickness 0.25mm, 100%
Bi
GF71570550
Bismuth, foil, 25x25mm, thickness 0.5mm, 100%
Bi
GF58555581
Bismuth, foil, 25x25mm, thickness 1.0mm, 100%
Bi
GF52383506
Bismuth, foil, 25x25mm, thickness 1.0mm, 99.97%
Bi
GF31001960
Bismuth, foil, 25x25mm, thickness 2.0mm, 100%
Bi
GF39813419
Bismuth, foil, 50x50mm, thickness 0.25mm, 100%
Bi
GF46319340
Bismuth, foil, 50x50mm, thickness 0.5mm, 100%
Bi
GF19448017
Bismuth, foil, 50x50mm, thickness 1.0mm, 100%
Bi
GF97656238
Bismuth, foil, 50x50mm, thickness 1.0mm, 99.97%
Bi
GF75246183
Bismuth, foil, 50x50mm, thickness 2.0mm, 100%
Bi
GF46489135
Bismuth, foil, light tested, 25x25mm, thickness 0.015mm, permanent polyester support, 99.97%
Bi
GF86892441
Bismuth, foil, light tested, 25x25mm, thickness 0.01mm, permanent polyester support, 99.97%
Bi
GF40931546
Bismuth, foil, light tested, 25x25mm, thickness 0.025mm, permanent polyester support, 99.97%
Bi
GF35246831
Bismuth, foil, light tested, 25x25mm, thickness 0.02mm, permanent polyester support, 99.97%
Bi
GF95571995
Bismuth, foil, light tested, 25x25mm, thickness 0.05mm, permanent polyester support, 99.97%
Bi
GF12550935
Bismuth, foil, light tested, 50x50mm, thickness 0.015mm, permanent polyester support, 99.97%
Bi
GF09655263
Bismuth, foil, light tested, 50x50mm, thickness 0.01mm, permanent polyester support, 99.97%
Bi
GF71673060
Bismuth, foil, light tested, 50x50mm, thickness 0.025mm, permanent polyester support, 99.97%
Bi
GF09816307
Bismuth, foil, light tested, 50x50mm, thickness 0.02mm, permanent polyester support, 99.97%
Bi
GF91742328
Bismuth, foil, light tested, 50x50mm, thickness 0.05mm, permanent polyester support, 99.97%
Bi
GF24083692
Bismuth, foil, not light tested, 100x100mm, thickness 0.015mm, permanent polyester support, 99.97%
Bi
GF77293592
Bismuth, foil, not light tested, 100x100mm, thickness 0.01mm, permanent polyester support, 99.97%
Bi
GF93912891
Bismuth, foil, not light tested, 100x100mm, thickness 0.025mm, permanent polyester support, 99.97%
Bi
GF19216087
Bismuth, foil, not light tested, 100x100mm, thickness 0.02mm, permanent polyester support, 99.97%
Bi