EMAIL THIS PAGE TO A FRIEND

Dalton transactions (Cambridge, England : 2003)

Quinolones and non-steroidal anti-inflammatory drugs interacting with copper(II), nickel(II), cobalt(II) and zinc(II): structural features, biological evaluation and perspectives.


PMID 23529676

Abstract

The structural features of copper(II), nickel(II), cobalt(II) and zinc(II) complexes with the antimicrobial drugs quinolones and non-steroidal anti-inflammatory drugs (NSAIDs) as ligands are discussed. The binding properties of these complexes to biomolecules (calf-thymus DNA, bovine or human serum albumin) are presented and evaluated. The biological activity (antimicrobial, antioxidant and antiproliferative) of selected complexes is investigated. Further perspectives concerning the synthesis and the biological activity of novel complexes with quinolones or NSAIDs attractive to synthetic chemists, biochemists and/or biologists are presented.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

60784
Cobalt, puriss. p.a., ≥99.8%, powder
Co
266698
Cobalt, foil, thickness 1.0 mm, ≥99.99%
Co
356891
Cobalt, foil, thickness 1.0 mm, 99.95% trace metals basis
Co
266671
Cobalt, foil, thickness 0.25 mm, ≥99.99% trace metals basis
Co
356875
Cobalt, foil, thickness 0.25 mm, 99.95%
Co
326380
Cobalt, foil, thickness 0.1 mm, ≥99.99%
Co
356867
Cobalt, foil, thickness 0.1 mm, 99.95% trace metals basis
Co
203076
Cobalt, granular, 99.995% trace metals basis
Co
266655
Cobalt, pieces, 99.5% trace metals basis
Co
266647
Cobalt, powder, <150 μm, ≥99.9% trace metals basis
Co
266639
Cobalt, powder, 2 μm particle size, 99.8% trace metals basis
Co
266663
Cobalt, rod, diam. 5.0 mm, 99.998% trace metals basis
Co
398810
Cobalt, rod, diam. 5.0 mm, 99.95% trace metals basis
Co
357057
Cobalt, wire, diam. 2.0 mm, ≥99.9%
Co
266701
Cobalt, wire, diam. 1.0 mm, 99.995% trace metals basis
Co
523453
Cobalt, wire, diam. 0.25 mm, 99.995%
Co
GF94594450
Cobalt, foil, 25mm disks, thickness 0.25mm, as rolled, 99.9%
Co
GF41541476
Cobalt, foil, 25mm disks, thickness 0.25mm, as rolled, 99.99+%
Co
GF45372315
Cobalt, foil, 4mm disks, thickness 0.003mm, 99.9%
Co
GF08560289
Cobalt, foil, 4mm disks, thickness 0.004mm, 99.9%
Co
GF89559343
Cobalt, foil, 4mm disks, thickness 0.005mm, 99.9%
Co
GF48392051
Cobalt, foil, 4mm disks, thickness 0.006mm, 99.9%
Co
GF55954873
Cobalt, foil, 4mm disks, thickness 0.007mm, 99.9%
Co
GF92926727
Cobalt, foil, 4mm disks, thickness 0.008mm, 99.9%
Co
GF70445246
Cobalt, foil, 4mm disks, thickness 0.009mm, 99.9%
Co
GF40089225
Cobalt, foil, 4mm disks, thickness 0.0125mm, 99.9%
Co
GF12485213
Cobalt, foil, 100x100mm, thickness 0.125mm, annealed, 99.9%
Co
GF48813723
Cobalt, foil, 100x100mm, thickness 0.125mm, annealed, 99.9%
Co
GF10782121
Cobalt, foil, 100x100mm, thickness 0.125mm, as rolled, 99.99+%
Co
GF40808516
Cobalt, foil, 100x100mm, thickness 0.25mm, as rolled, 99.9%
Co