EMAIL THIS PAGE TO A FRIEND

Atherosclerosis

Association between HMW adiponectin, HMW-total adiponectin ratio and early-onset coronary artery disease in Chinese population.


PMID 24929819

Abstract

Adiponectin is an adipose-secreting protein that shows atheroprotective property and has inverse relation with coronary artery disease (CAD). High-molecular weight (HMW) adiponectin is reported as the active form of adiponectin. In the present study, we aimed to investigate the association between total adiponectin, HMW adiponectin, HMW-total adiponectin ratio and the severity of coronary atherosclerosis, and to compare their evaluative power for the risk of CAD. Serum levels of total and HMW adiponectin were measured in 382 early-onset CAD (EOCAD) patients and 305 matched controls undergoing coronary angiography by enzyme-linked immunosorbent assay (ELISA). Gensini score was used to evaluate the severity of coronary atherosclerosis. CAD onset age was positively correlated with HMW adiponectin (rxa0=xa00.383, Pxa0

Related Materials