EMAIL THIS PAGE TO A FRIEND

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

Serial intravascular ultrasound observations from the Tryton first-in-man study.


PMID 25138185

Abstract

To report serial intravascular ultrasound (IVUS) findings of bifurcation lesions treated with the dedicated Tryton Side Branch Stent to assess mechanisms of restenosis. The Tryton FIM study was a multicentre, prospective, single-arm, "first-in-man" study to treat de novo bifurcation lesions. Minimum lumen area (MLA) sites and overall volumes were analysed within main vessels and side branches. Overall, 27 main vessels and 22 side branches had paired baseline and follow-up IVUS. The post-intervention main vessel MLA decreased from 5.3 (4.1, 6.2) to 4.8 (3.4, 5.7) mm2 at follow-up, p=0.02, and the side branch MLA decreased from 3.5 (3.0, 3.8) to 2.5 (2.2, 3.2) mm2, p=0.0005. Stent area at the side branch did not change (mean stent area from 4.0 [3.3, 4.1] to 3.8 [3.4, 4.2] mm3/mm, p=0.95). Neointimal hyperplasia (NIH) net volume obstruction (%) measured 1.8% (0.5, 7.0) for the entire main vessel and 14.9% (2.3, 31.1) for the entire side branch stents. In both main vessel and side branches the decrease in lumen area correlated significantly with NIH. Serial IVUS analysis of a new side branch Tryton stent showed no chronic stent recoil. Side branch underexpansion was common and along with superimposed NIH contributed to the reduction in lumen dimensions at follow-up.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

27066
Chromium, coating quality, 99.95%, grit
Cr
374849
Chromium, chips, 99.995% trace metals basis
Cr
255610
Chromium, chips, thickness ~2 mm, 99.5%
Cr
229563
Chromium, chunks, ≥99.99% trace metals basis
Cr
266264
Chromium, powder, 99.5%, −100 mesh
Cr
266299
Chromium, powder, ≥99% trace metals basis, −325 mesh
Cr
749052
Chromium, sputtering target, diam. × thickness 3.00 in. × 0.125 in., 99.95% trace metals basis
Cr
GF97385338
Chromium, foil, not light tested, 100x100mm, thickness 0.02mm, permanent polyester support, 99.99+%
Cr
GF23770885
Chromium, foil, not light tested, 100x100mm, thickness 0.03mm, permanent polyester support, 99.99+%
Cr
GF24605816
Chromium, foil, not light tested, 100x100mm, thickness 0.04mm, permanent polyester support, 99.99+%
Cr
GF22618739
Chromium, foil, not light tested, 100x100mm, thickness 0.05mm, permanent polyester support, 99.99+%
Cr
GF00270593
Chromium, foil, not light tested, 25x25mm, thickness 0.0015mm, permanent polyester support, 99.99+%
Cr
GF88955410
Chromium, foil, not light tested, 25x25mm, thickness 0.001mm, permanent polyester support, 99.99+%
Cr
GF94865170
Chromium, foil, not light tested, 25x25mm, thickness 0.0025mm, permanent polyester support, 99.99+%
Cr
GF73692377
Chromium, foil, not light tested, 25x25mm, thickness 0.002mm, permanent polyester support, 99.99+%
Cr
GF61658725
Chromium, foil, not light tested, 25x25mm, thickness 0.003mm, permanent polyester support, 99.99+%
Cr
GF81124286
Chromium, foil, not light tested, 25x25mm, thickness 0.004mm, permanent polyester support, 99.99+%
Cr
GF05241316
Chromium, foil, not light tested, 25x25mm, thickness 0.005mm, permanent polyester support, 99.99+%
Cr
GF98123250
Chromium, foil, not light tested, 25x25mm, thickness 0.006mm, permanent polyester support, 99.99+%
Cr
GF34438923
Chromium, foil, not light tested, 25x25mm, thickness 0.007mm, permanent polyester support, 99.99+%
Cr
GF49392456
Chromium, foil, not light tested, 25x25mm, thickness 0.009mm, permanent polyester support, 99.99+%
Cr
GF88985446
Chromium, foil, not light tested, 25x25mm, thickness 0.0125mm, permanent polyester support, 99.99+%
Cr
GF30096053
Chromium, foil, not light tested, 25x25mm, thickness 0.015mm, permanent polyester support, 99.99+%
Cr
GF12477157
Chromium, foil, not light tested, 25x25mm, thickness 0.01mm, permanent polyester support, 99.99+%
Cr
GF84397168
Chromium, foil, not light tested, 25x25mm, thickness 0.025mm, permanent polyester support, 99.99+%
Cr
GF50354692
Chromium, foil, not light tested, 25x25mm, thickness 0.02mm, permanent polyester support, 99.99+%
Cr
GF74347050
Chromium, foil, not light tested, 25x25mm, thickness 0.03mm, permanent polyester support, 99.99+%
Cr
GF07622759
Chromium, foil, 50x50mm, thickness 3.0mm, hard, 99.95%
Cr
GF35390651
Chromium, foil, light tested, 25x25mm, thickness 0.015mm, permanent polyester support, 99.99+%
Cr
GF46122645
Chromium, foil, not light tested, 25x25mm, thickness 0.04mm, permanent polyester support, 99.99+%
Cr