EMAIL THIS PAGE TO A FRIEND

Environmental science and pollution research international

Occurrence and distribution of sulfonamides, tetracyclines, quinolones, macrolides, and nitrofurans in livestock manure and amended soils of Northern China.


PMID 25318415

Abstract

A feasible and rapid analysis for the simultaneous determination of sulfonamides (SAs), tetracyclines (TCs), fluoroquinolones (FQs), macrolides (MACs) and nitrofurans (NFs) in livestock manure and soils was established by solid-phase extraction (SPE)-ultra-performance liquid chromatography (UPLC)-tandem mass spectrometry (MS/MS). A total of 32 manure and 17 amended soil samples from the Liaoning and Tianjin areas in Northern China were collected for analysis. The largest detected frequencies and concentrations in manure samples were those of TCs (3326.6 ± 12,302.6 μg/kg), followed by FQs (411.3 ± 1453.4 μg/kg), SAs (170.6 ± 1060.2 μg/kg), NFs (85.1 ± 158.1 μg/kg), and MACs (1.4 ± 4.8 μg/kg). In general, veterinary antibiotics (VAs) were detected with higher concentrations in swine and chicken manure than in cattle manure, reflecting the heavy usage of VAs in swine and chicken husbandry in the studied area. Furthermore, higher residues of antibiotics were found in piglet and fattening swine manure than in sow manure. In addition, TCs were the most frequently (100%) detected antibiotics in amended soil with higher concentrations (up to 10,967.1 μg/kg) than any other VAs. The attenuation of SAs was more obvious than TCs in amended soil after fertilization, which can most likely be attributed to the stronger sorption of TCs than SAs to soil organic matter through cation exchange. This study illustrated the prevalence of TCs detected in both animal manure and fertilized agricultural soils in Northern China, which may increase the risk to human health through the food chain. Thus, TCs should be given more attention in the management of veterinary usage in livestock husbandry.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

17776
Chlortetracycline Selective Supplement, for microbiology
C22H23ClN2O8
F9505
Furazolidone
C8H7N3O5
46297
Furazolidone, VETRANAL, analytical standard
C8H7N3O5
33703
Ofloxacin, VETRANAL, analytical standard
C18H20FN3O4
1478108
Ofloxacin, United States Pharmacopeia (USP) Reference Standard
C18H20FN3O4
PHR1168 Ofloxacin, Pharmaceutical Secondary Standard; Certified Reference Material
C18H20FN3O4
32072
Simeton, PESTANAL®, analytical standard
C8H15N5O
S8626
Sulfadiazine, ≥99.0%
C10H10N4O2S
35033
Sulfadiazine, VETRANAL, analytical standard
C10H10N4O2S
1625009
Sulfadiazine, United States Pharmacopeia (USP) Reference Standard
C10H10N4O2S
S1800000
Sulfadiazine, European Pharmacopoeia (EP) Reference Standard
C10H10N4O2S
PHR1343
Sulfadiazine, Pharmaceutical Secondary Standard; Certified Reference Material
C10H10N4O2S
Y0001480
Sulfadiazine for identification of impurity F, European Pharmacopoeia (EP) Reference Standard
C10H10N4O2S
S1900000
Sulfadimidine, European Pharmacopoeia (EP) Reference Standard
C12H14N4O2S
Y0001495
Sulfadimidine for peak identification, European Pharmacopoeia (EP) Reference Standard
C12H14N4O2S
00189
Sulfadimidine solution, 1 mg/mL in H2O
C12H14N4O2S
S6256
Sulfamethazine, ≥99%
C12H14N4O2S
46802
Sulfamethazine, VETRANAL, analytical standard
C12H14N4O2S
S7507
Sulfamethoxazole, analytical standard
C10H11N3O3S
76177
Sulfamethoxazole, certified reference material, TraceCERT®
C10H11N3O3S
31737
Sulfamethoxazole, VETRANAL, analytical standard
C10H11N3O3S
PHR1126
Sulfamethoxazole, Pharmaceutical Secondary Standard; Certified Reference Material
C10H11N3O3S
1631001
Sulfamethoxazole, United States Pharmacopeia (USP) Reference Standard
C10H11N3O3S
S2100000
Sulfamethoxazole, European Pharmacopoeia (EP) Reference Standard
C10H11N3O3S
S0508
Sulfamonomethoxine
C11H12N4O3S
32091
Sulfamonomethoxine, VETRANAL, analytical standard
C11H12N4O3S