EMAIL THIS PAGE TO A FRIEND

Nutrients

The effect on selenium concentrations of a randomized intervention with fish and mussels in a population with relatively low habitual dietary selenium intake.


PMID 25599275

Abstract

Selenium status of the Danish population is below that assumed optimal for the suggested protective effects against chronic diseases, including certain cancers. Fish and shellfish are important dietary sources of selenium in Denmark. We investigated the effect of increased fish and mussel intake on selenium blood concentrations in a population with relatively low habitual dietary selenium intake. We randomly assigned 102 healthy men and women (all non-smokers) aged 48-76 years to an intervention group (n = 51) or a control group (n = 51). Intervention participants received 1000 g fish and mussels/week for 26 weeks (~50 μg selenium/day). Controls received no intervention. Non-fasting blood samples were taken and whole blood selenium was determined using inductively coupled plasma-mass spectrometry (ICP-MS), and plasma selenoprotein P (SelP) was determined by high performance liquid chromatography coupled to ICP-MS. All available observations were included in linear multiple regression analysis to evaluate the effect of the intervention. The difference in mean change for intervention compared with control persons was 14.9 ng/mL (95% CI: 10.2, 19.7) for whole blood selenium, and 7.0 ng/mL (95% CI: 3.1, 10.9) for plasma SelP (Weeks 0-26). Selenium concentrations were significantly increased after 26 weeks of intervention, albeit to a lower degree than expected.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

A3795
Ammonium nitrate, plant cell culture tested
H4N2O3
A9642
Ammonium nitrate, ≥99.0%
H4N2O3
256064
Ammonium nitrate, 99.999% trace metals basis
H4N2O3
221244
Ammonium nitrate, ACS reagent, ≥98%
H4N2O3
A7455
Ammonium nitrate, BioXtra, ≥99.5%
H4N2O3
09890
Ammonium nitrate, puriss. p.a., ACS reagent, ≥99.0% (T)
H4N2O3
31114
Ammonium nitrate, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥98%
H4N2O3
804819
Ammonium nitrate, anhydrous, free-flowing, Redi-Dri, ACS reagent, ≥98%
H4N2O3
357340
Rhodium, foil, thickness 0.025 mm, 99.9% trace metals basis
Rh
204218
Rhodium, powder, 99.95% trace metals basis
Rh
267368
Rhodium, sponge, 99.9% trace metals basis
Rh
277916
Rhodium, wire, diam. 1.0 mm, 99.9% trace metals basis
Rh
GF94930667
Rhodium, microfoil, disks, 10mm, thinness 0.25μm, specific density 310μg/cm2, permanent mylar 3.5μm support, 99.99%
Rh
GF64213680
Rhodium, wire reel, 0.05m, diameter 0.12mm, as drawn, 99.9%
Rh
GF37380089
Rhodium, wire reel, 0.2m, diameter 0.25mm, hard, 99.9%
Rh
GF45819995
Rhodium, wire reel, 0.05m, diameter 0.25mm, hard, 99.9%
Rh
GF83497652
Rhodium, wire reel, 0.05m, diameter 1.0mm, as drawn, 99.9%
Rh
GF26710680
Rhodium, wire reel, 0.1m, diameter 0.12mm, as drawn, 99.9%
Rh
GF27499045
Rhodium, wire reel, 0.1m, diameter 0.25mm, hard, 99.9%
Rh
GF06539979
Rhodium, wire reel, 0.1m, diameter 0.5mm, as drawn, 99.9%
Rh
GF37207166
Rhodium, wire reel, 0.1m, diameter 1.0mm, as drawn, 99.9%
Rh
GF38835737
Rhodium, wire reel, 0.2m, diameter 0.12mm, as drawn, 99.9%
Rh
GF17496973
Rhodium, wire reel, 0.2m, diameter 0.5mm, as drawn, 99.9%
Rh
GF54466937
Rhodium, wire reel, 0.5m, diameter 0.12mm, as drawn, 99.9%
Rh
GF72510364
Rhodium, wire reel, 0.5m, diameter 0.25mm, hard, 99.9%
Rh
GF44569907
Rhodium, foil, 25x25mm, thickness 0.125mm, as rolled, 99.9%
Rh
GF80841146
Rhodium, foil, 25x25mm, thickness 0.15mm, as rolled, 99.9%
Rh
GF40539405
Rhodium, foil, 25x25mm, thickness 0.1mm, as rolled, 99.9%
Rh
GF20569697
Rhodium, foil, 12mm disks, thickness 0.5mm, as rolled, 99.9%
Rh
GF61934429
Rhodium, foil, 12mm disks, thickness 1.0mm, as rolled, 99.9%
Rh