EMAIL THIS PAGE TO A FRIEND

Bioorganic & medicinal chemistry

Synthesis of (+)-crocacin D and simplified bioactive analogues.


PMID 25638500

Abstract

The total synthesis of (+)-crocacin D has been achieved in 15 steps (9 isolated intermediates) and 14% overall yield from commercially available starting materials and using (+)-crocacin C as a key intermediate. A number of simplified analogues and their biological activities are also reported.