EMAIL THIS PAGE TO A FRIEND

Cognition & emotion

On the relationship between negative affective priming and prefrontal cognitive control mechanisms.


PMID 25648386

Abstract

Although several studies have examined inhibition of affective stimuli, valence-dependent cognitive control effects remain poorly understood. Behavioural and functional imaging (functional magnetic resonance imaging) data were collected from 17 healthy participants to examine neural correlates of the Negative Affective Priming (NAP) task. We created relative ratio scores considering the reaction times of prime trials in order to assess the amount of interference after the presentation of negative and positive distracter words. Behavioural results showed an attenuated NAP effect for negative distracters compared to neutral stimuli. Furthermore, priming negative distracters generated more interference by reacting to the probe target than positive distracters. Neuroimaging data revealed a stronger prefrontal activation during negative NAP trials compared to positive NAP and neutral control trials, which was reflected in a heightened activation of superior and middle frontal gyrus as well as parietal cortex. The findings show the impact of negative distracters on prefrontal response, contributing to the understanding of NAP effects in healthy subjects.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

01423
N-Acetyl-D-penicillamine, for HPLC derivatization, ≥99.0% (T)
C7H13NO3S