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Vox sanguinis

Persistent aggregates in apheresis platelet concentrates.


PMID 25754290

Abstract

Aggregates often appear during apheresis. Sometimes, these persist throughout storage, causing product wastage. This study assessed product quality of apheresis concentrates containing persistent aggregates (PA) and aimed to identify the factors that contribute to their formation. Donation (nxa0=xa0180) and platelet indices (nxa0≥xa010) from apheresis concentrates with PA were compared with aggregate-free products. The proportion of donors with at least one previous PA donation was twofold higher in the PA group (Pxa0