EMAIL THIS PAGE TO A FRIEND

Advanced healthcare materials

Microfluidic Chip for Site-Specific Neuropharmacological Treatment and Activity Probing of 3D Neuronal "Optonet" Cultures.


PMID 25953011

Abstract

The study introduces a "brain-on-a-chip" microfluidic platform that hosts brain-like 3D cultures ("optonets") whose activity and responses to flowing drugs are recorded optically. Optonets are viable, optically accessible 3D neural networks whose characteristics approximate cortical networks. The results demonstrate the ability to monitor complex 3D activity patterns during extended site-specific, reversible neuropharmacogical exposure, suggesting an interesting potential in drug screening.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

235709
Octamethyltrisiloxane, 98%
C8H24O2Si3
E9379
Stains-All, ~95%
C30H27BrN2S2
230960
Stains-All, Dye content 95 %
C30H27BrN2S2