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Developmental cell

Adhesive Enrichment and Membrane Turnover at the Heart of Cardiopharyngeal Induction.


PMID 26374763

Abstract

Differential inductive signaling during asymmetric division of progenitor cells specifies the heart lineage in Ciona intestinalis. In this issue of Developmental Cell, Cota and Davidson (2015) show that differential induction is mediated by FGF receptor regionalization, resulting from asymmetric cell-matrix adhesion and reduced mitotic turnover of polarized Caveolin-rich membrane domains.