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Biological trace element research

Arginine Silicate Inositol Complex Accelerates Cutaneous Wound Healing.


PMID 27743199

Abstract

Arginine silicate inositol (ASI) complex is a composition of arginine, silicon, and inositol that has been shown to have beneficial effects on vascular health. This study reports the effects of an ASI ointment on wound healing in rats. A full-thickness excision wound was created by using a disposable 5xa0mm diameter skin punch biopsy tool. In this placebo-controlled study, the treatment group's wound areas were covered by 4 or 10xa0% ASI ointments twice a day for 5, 10, or 15xa0days. The rats were sacrificed either 5, 10, or 15xa0days after the wounds were created, and biopsy samples were taken for biochemical and histopathological analysis. Granulation tissue appeared significantly faster in the ASI-treated groups than in the control groups (Pxa0