EMAIL THIS PAGE TO A FRIEND

Journal of chromatography. B, Biomedical sciences and applications

In vitro and in vivo metabolism of myristicin in the rat.


PMID 9521577

Abstract

Myristicin [5-allyl-1-methoxy-2,3-(methylenedioxy)benzene] is a flavoring plant constituent and has been known to produce significant psychopharmacological responses as well as insecticidal activity. From in vitro and in vivo metabolism of myristicin, the two metabolites 5-allyl-1-methoxy-2,3-dihydroxybenzene and 1'-hydroxymyristicin were identified using GC-MS after derivatization of sample matrices with a mixture of BSTFA-TMCS. Those metabolites from in vitro study were also confirmed in urine after an oral administration of myrisitcin to rats, and enzymatic hydrolysis of urine suggested that these metabolites were excreted as conjugated forms as well.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

M9411
Myristicin from parsley leaf oil, ≥85% (HPLC), oil
C11H12O3