Synonym: Quinine sulfate (2:1) (salt) dihydrate
|Related Categories||Alkaloid, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antiparasitic / Antiprotozoal / Anthelminthic,|
|optical activity||[α]25/D −229°, c = 2 in 0.1 M HCl|
|mp||~225 °C (dec.)(lit.)|
|233-235 °C (dec.)|
Contains hydroquinine sulfate monohydrate
10 g in poly bottle
Potassium channel blocker. Antimalarial, anticholinergic, antihypertensive, and hypoglycemic agent; alkaloid originally isolated from the Cinchona family of South American trees. Inhibits mitochondrial ATP-regulated potassium channel. Used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.
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suitable for fluorescence, anhydrous, ≥98.0% (dried material, NT)
synthetic, ≥90% (HPLC)
meets USP testing specifications, monograph mol wt. 782.94 ((C20H24N2O2)2 . H2SO4 . 2H2O)
Certificate of Analysis
|Precautionary statements||P261-P305 + P351 + P338|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Gloves|
|Hazard Codes (Europe)||Xi|
|Risk Statements (Europe)||36/37/38|
|Safety Statements (Europe)||26|
Cinchona alkaloids and their derivatives have proven to catalyze an astonishing array of enantioselective transformations, providing access to chiral products of high enantiopurity.1 The presence of ...
William Sommer and Daniel Weibel
Aldrich ChemFiles 2008, 8.2, 74.
Keywords: Addition reactions, Aminations, Antimicrobials, Asymmetric synthesis, Catalysis, Desymmetrizations, Dihydroxylations, Ligands, Reductive aminations
Aldrich MSDS 1, 1580:A / Corp MSDS 1 (2), 3023:D / FT-IR 1 (2), 865:C / FT-IR 2 (3), 3922:A / IR-Spectra (3), 1392:D / IR-Spectra (2), 1213:H / RegBook 1 (2), 2623:L / Sigma FT-IR 1 (1), 600:D / Structure Index 1, 414:C:2
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