Synonym: DEP, DEPC, Diethyl dicarbonate, Diethyl oxydiformate, Ethoxyformic acid anhydride
|Related Categories||Alternative Energy, Building Blocks, Carbonates, Carbonyl Compounds, Chemical Synthesis,|
|bp||93-94 °C/18 mmHg(lit.)|
|density||1.101 g/mL at 25 °C(lit.)|
Modification reagent for His and Tyr residues in proteins. Robust probe for structural disruptions in dsDNA, reacting with fully or partially unstacked bases.1
Utilized as an antimicrobial additive, a ribonuclease inhibitor, a histidine residue modifier, and as a reagent for conversion of imines to carbamates.
Inactivates RNase in solution at about 0.1% (v/v), thus protecting RNA against degradation.
25, 100 g in poly bottle
5 g in glass bottle
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P261-P305 + P351 + P338|
|Personal Protective Equipment||Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter|
|Hazard Codes (Europe)||Xn|
|Risk Statements (Europe)||22-36/37/38|
|Safety Statements (Europe)||26-36|
|RIDADR||NA 1993 / PGIII|
|Flash Point(F)||156.2 °F|
|Flash Point(C)||69 °C|
Research and development of solid-state lithium fast-ion conductors is crucial because they can be potentially used as solid electrolytes in all-solid-state batteries, which may solve the safety and ...
Motoaki Matsuo,1 Hiroyuki Oguchi,1,2 Hideki Maekawa,2 Hitoshi Takamura,2Shin-ichi Orimo,1*
Material Matters Volume 5 Article 4
Keywords: Calorimetry, Deposition, Diffraction, Diffusion, Melting, Nuclear magnetic resonance spectroscopy, Raman spectroscopy, Spectroscopy, Substitutions, X-Ray diffraction, transformation
Food Sci. Technol. 57, 343, (1993)
Tetrahedron 48, 3445, (1992)
Substrate-induced conformational changes in sarcoplasmic reticulum Ca2+-ATPase probed by surface modification using diethylpyrocarbonate with mass spectrometry. Narumi R, Yamamoto T, Inoue A, et al. FEBS Lett. 586(19), 3172-8, (2012)
Heterologous production and characterisation of two distinct dihaem-containing membrane integral cytochrome b(561) enzymes from Arabidopsis thaliana in Pichia pastoris and Escherichia coli cells. Cenacchi L, Busch M, Schleidt PG, et al. Biochim. Biophys. Acta 1818(3), 679-88, (2012)
Outcome analysis of trapezectomy with and without pyrocarbon interposition to treat primary arthrosis of the trapeziometacarpal joint. Colegate-Stone TJ, Garg S, Subramanian A, et al. Hand Surg. 16(1), 49-54, (2011)
One octarepeate expansion to the human prion protein alters both the Zn2+ and Cu2+ coordination environments within the octarepeate domain. Shearer J, Rosenkoetter KE, Callan PE, et al. Inorg. Chem. 50(4), 1173-5, (2011)
Chemical modification of the Rieske protein from Thermus thermophilus using diethyl pyrocarbonate modifies ligating histidine 154 and reduces the [2FE-2S] cluster. Konkle ME, Elsenheimer KN, Hakala K, et al. Biochemistry 49(34), 7272-81, (2010)
Identification of histidine residues involved in Zn(2+) binding to αA- and αB-crystallin by chemical modification and MALDI TOF mass spectrometry. Karmakar S and Das KP Protein J. 31(7), 623-40, (2012)
Inhibitory effect of zinc on the absorption of JBP485 via the gastrointestinal oligopeptide transporter (PEPT1) in rats. Miao Q, Liu Q, Wang C, et al. Drug Metab. Pharmacokinet. 26(5), 494-502, (2011)
Fermentation of barley by using Saccharomyces cerevisiae: examination of barley as a feedstock for bioethanol production and value-added products. Amera Gibreel et al Appl. Environ. Microbiol. 75, 1363-72, (2009)
Sambrook, J., et al. Molecular Cloning: A Laboratory Manual 2nd ed., Plainview, NY , (1989), 7.3-7.4
Aldrich MSDS 1, 681:A / Corp MSDS 1 (1), 1224:A / FT-IR 2 (1), 977:A / FT-IR 1 (1), 611:B / FT-NMR 1 (1), 929:C / IR-Spectra (3), 365:C / IR-Spectra (2), 325:A / NMR-Reference 2 (1), 517:A / RegBook 1 (1), 695:F / Sax 6, 1390 / Sigma FT-IR 1 (2), 466:C / Structure Index 1, 105:B:6 / Vapor Phase 3, 634:C
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