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449881 Aldrich

Lithium chloride

anhydrous, beads, −10 mesh, ≥99.9% trace metals basis

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Properties

Related Categories 3: Li, Beaded Materials, Chemical Synthesis, Crystal Grade Inorganics, Essential Chemicals,
grade   anhydrous
assay   ≥99.9% trace metals basis
form   beads
particle size   −10 mesh
bp   1383 °C/1 atm(lit.)
mp   605 °C(lit.)
solubility   acetone: soluble(lit.)
  ethanol: soluble(lit.)
  pyridine: soluble(lit.)

Description

Packaging

10, 50 g in ampule

Application

Used in formation of an active Mn(0) species useful for radical cyclization reactions.1

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.




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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
Hazard Codes (Europe) 
Xn
Risk Statements (Europe) 
Safety Statements (Europe) 
26-36/37/39
WGK Germany 
3
RTECS 
OJ5950000

Protocols & Articles

Articles

Complex Hydrides: A New Category of Solid-state Lithium Fast-ion Conductors

Research and development of solid-state lithium fast-ion conductors is crucial because they can be potentially used as solid electrolytes in all-solid-state batteries, which may solve the safety and ...
Motoaki Matsuo,1 Hiroyuki Oguchi,1,2 Hideki Maekawa,2 Hitoshi Takamura,2Shin-ichi Orimo,1*
Material Matters Volume 5 Article 4
Keywords: Calorimetry, Deposition, Diffraction, Diffusion, Melting, Nuclear magnetic resonance spectroscopy, Raman spectroscopy, Search, Spectra, Spectroscopy, Substitutions, Support, X-Ray diffraction, transformation

Peer-Reviewed Papers

References

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1. Tang, J. et al. Tetrahedron 55, 1893, (1999)

Chemical genetics reveals a complex functional ground state of neural stem cells Diamandis, P., et. al. Nat. Chem. Biol. 3(5), 268-273, (2007)

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Inhibition of glycogen synthase kinase 3β promotes tight junction stability in brain endothelial cells by half-life extension of occludin and claudin-5. Ramirez SH, Fan S, Dykstra H, et al. PLoS ONE 8(2), e55972, (2013)

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Lithium chloride and inhibition of glycogen synthase kinase 3β as a potential therapy for serous ovarian cancer. Novetsky AP, Thompson DM, Zighelboim I, et al. Int. J. Gynecol. Cancer 23(2), 361-6, (2013)

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Active beta-catenin signaling is an inhibitory pathway for human immunodeficiency virus replication in peripheral blood mononuclear cells. Kumar A J. Virol. 82(6), 2813-20, (2008)

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Switching reversibility to irreversibility in glycogen synthase kinase 3 inhibitors: clues for specific design of new compounds. Daniel I Perez et al J. Med. Chem. 54, 4042-56, (2011)

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Anti-obesity effects of 3-hydroxychromone derivative, a novel small-molecule inhibitor of glycogen synthase kinase-3. Lee S, Yang WK, Song JH, et al. Biochem. Pharmacol. 85(7), 965-76, (2013)

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On the existence of "L-threonine formate", "L-alanine lithium chloride" and "bis L-alanine lithium chloride" crystals. Petrosyan AM, Ghazaryan VV, and Fleck M Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 105, 623-5, (2013)

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Dose-dependent nuclear β-catenin response segregates endomesoderm along the sea star primary axis. McCauley BS, Akyar E, Saad HR, et al. Development 142(1), 207-17, (2015)

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In-silico identification and characterization of organic and inorganic chemical stress responding genes in yeast (Saccharomyces cerevisiae). Barozai MY, Bashir F, Muzaffar S, et al. Gene 550(1), 74-80, (2014)

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Bacterial maximum non-inhibitory and minimum inhibitory concentrations of different water activity depressing solutes. Cebrián G, Arroyo C, Mañas P, et al. Int. J. Food Microbiol. 188, 67-74, (2014)

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Enhancement of Runx2 expression is potentially linked to β-catenin accumulation in canine intervertebral disc degeneration. Iwata M, Aikawa T, Hakozaki T, et al. J. Cell Physiol. 230(1), 180-90, (2015)

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The Cdc42/Rac nucleotide exchange factor protein β1Pix (Pak-interacting exchange factor) modulates β-catenin transcriptional activity in colon cancer cells: evidence for direct interaction of β1PIX with β-catenin. Chahdi A and Raufman JP J. Biol. Chem. 288(47), 34019-29, (2013)

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Reliability of lithium dilution cardiac output in anaesthetized sheep. Axiak Flammer SM, Critchley LA, Weber A, et al. Br. J. Anaesth. 111(5), 833-9, (2013)

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Real-time in vivo monitoring of circadian E-box enhancer activity: a robust and sensitive zebrafish reporter line for developmental, chemical and neural biology of the circadian clock. Weger M, Weger BD, Diotel N, et al. Dev. Biol. 380(2), 259-73, (2013)

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Role of glycogen synthase kinase-3β in ketamine-induced developmental neuroapoptosis in rats. Liu JR, Baek C, Han XH, et al. Br. J. Anaesth. 110 Suppl 1, i3-9, (2013)

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A framework for the establishment of a cnidarian gene regulatory network for "endomesoderm" specification: the inputs of ß-catenin/TCF signaling. Röttinger E, Dahlin P, and Martindale MQ PLoS Genet. 8(12), e1003164, (2012)

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The mood stabilizer valproate activates human FGF1 gene promoter through inhibiting HDAC and GSK-3 activities. Kao CY, Hsu YC, Liu JW, et al. J. Neurochem. 126(1), 4-18, (2013)

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Role of olfaction in the conditioned sucrose preference of sweet-ageusic T1R3 knockout mice. Steven Zukerman et al Chem. Senses 34, 685-94, (2009)

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Direct observation of the hole protonation state and hole localization site in DNA-oligomers. Amitava Adhikary et al J. Am. Chem. Soc. 131, 8614-9, (2009)

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Glucose-induced β-catenin acetylation enhances Wnt signaling in cancer. Chocarro-Calvo A, García-Martínez JM, Ardila-González S, et al. Mol. Cell. 49(3), 474-86, (2013)

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Preferential interactions between lithium chloride and glucan chains in N,N-dimethylacetamide drive cellulose dissolution. Gross AS, Bell AT, and Chu JW J. Phys. Chem. B 117(12), 3280-6, (2013)

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The similarity between human embryonic stem cell-derived epithelial cells and ameloblast-lineage cells. Zheng LW, Linthicum L, DenBesten PK, et al. Int. J. Oral Sci. 5(1), 1-6, (2013)

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Lithium chloride attenuates cell death in oculopharyngeal muscular dystrophy by perturbing Wnt/β-catenin pathway. Abu-Baker A, Laganiere J, Gaudet R, et al. Cell Death Dis. 4, e821, (2013)

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Nuclear factor-κB modulates osteogenesis of periodontal ligament stem cells through competition with β-catenin signaling in inflammatory microenvironments. Chen X, Hu C, Wang G, et al. Cell Death Dis. 4, e510, (2013)

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Palatable food avoidance and acceptance learning with different stressors in female rats. Liang NC, Smith ME, and Moran TH Neuroscience 235, 149-58, (2013)

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Kinetics and mechanism of imidazole-catalyzed acylation of cellulose in LiCl/N,N-dimethylacetamide. Nawaz H, Pires PA, and El Seoud OA Carbohydr. Polym. 92(2), 997-1005, (2013)

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Dexamethasone shifts bone marrow stromal cells from osteoblasts to adipocytes by C/EBPalpha promoter methylation. Li J, Zhang N, Huang X, et al. Cell Death Dis. 4, e832, (2013)

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Effects of the Ras homolog Rhes on Akt/protein kinase B and glycogen synthase kinase 3 phosphorylation in striatum. Harrison LM, Muller SH, and Spano D Neuroscience 236, 21-30, (2013)

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Are morphologic and functional consequences of status epilepticus in infant rats progressive? Kubová H and Mareš P Neuroscience 235, 232-49, (2013)

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Application of scaffolds for bone regeneration strategies: current trends and future directions. Billström GH, Blom AW, Larsson S, et al. Injury 44 Suppl 1, S28-33, (2013)

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Low-dose lithium uptake promotes longevity in humans and metazoans. Zarse K Eur. J. Nutr. 50(5), 387-9, (2011)

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Autocrine stimulation of osteoblast activity by Wnt5a in response to TNF-α in human mesenchymal stem cells. Briolay A, Lencel P, Bessueille L, et al. Biochem. Biophys. Res. Commun. 430(3), 1072-7, (2013)

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Lithium prevents early cytosolic calcium increase and secondary injurious calcium overload in glycolytically inhibited endothelial cells. Bosche B, Schäfer M, Graf R, et al. Biochem. Biophys. Res. Commun. 434(2), 268-72, (2013)

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Phosphorylation of amyloid precursor protein at threonine 668 is essential for its copper-responsive trafficking in SH-SY5Y neuroblastoma cells. Acevedo KM, Opazo CM, Norrish D, et al. J. Biol. Chem. 289(16), 11007-19, (2014)

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NR2B subunit of the NMDA glutamate receptor regulates appetite in the parabrachial nucleus. Wu Q, Zheng R, Srisai D, et al. Proc. Natl. Acad. Sci. U. S. A. 110(36), 14765-70, (2013)

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Fractionation and structural characterization of LiCl-DMSO soluble hemicelluloses from tomato. Assor C, Quemener B, Vigouroux J, et al. Carbohydr. Polym. 94(1), 46-55, (2013)

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Control of Hes7 expression by Tbx6, the Wnt pathway and the chemical Gsk3 inhibitor LiCl in the mouse segmentation clock. González A, Manosalva I, Liu T, et al. PLoS ONE 8(1), e53323, (2013)

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CG0009, a novel glycogen synthase kinase 3 inhibitor, induces cell death through cyclin D1 depletion in breast cancer cells. Kim HM, Kim CS, Lee JH, et al. PLoS ONE 8(4), e60383, (2013)

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Regulation of proteolytic cleavage of retinoid X receptor-α by GSK-3β. Gao W, Liu J, Hu M, et al. Carcinogenesis 34(6), 1208-15, (2013)

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Lithium attenuates IFN-β production and antiviral response via inhibition of TANK-binding kinase 1 kinase activity. Wang L, Zhang L, Zhao X, et al. J. Immunol. 191(8), 4392-8, (2013)

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Lithium chloride inhibits vascular smooth muscle cell proliferation and migration and alleviates injury-induced neointimal hyperplasia via induction of PGC-1α. Wang Z, Zhang X, Chen S, et al. PLoS ONE 8(1), e55471, (2013)

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Elimination of heparin interference during microarray processing of fresh and biobank-archived blood samples. Hebels DG, van Herwijnen MH, Brauers KJ, et al. Environ. Mol. Mutagen. 55(6), 482-91, (2014)

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Enhanced apoptotic effects by downregulating Mcl-1: evidence for the improvement of photodynamic therapy with Celecoxib. Song J, Chen Q, and Xing D Exp. Cell Res. 319(10), 1491-504, (2013)

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Inhibition of caudal fin regeneration in Corydoras aeneus by lithium chloride. Zarnescu O, Stavri S, and Moldovan L Micron 46, 66-75, (2013)

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Effects of transcranial focal electrical stimulation alone and associated with a sub-effective dose of diazepam on pilocarpine-induced status epilepticus and subsequent neuronal damage in rats. Besio W, Cuellar-Herrera M, Luna-Munguia H, et al. Epilepsy Behav. 28(3), 432-6, (2013)

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Effect of lithium chloride and antineoplastic drugs on survival and cell cycle of androgen-dependent prostate cancer LNCap cells. Azimian-Zavareh V, Hossein G, and Janzamin E Indian J. Pharmacol. 44(6), 714-21, (2012)

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Lithium ameliorates open-field and elevated plus maze behaviors, and brain phospho-glycogen synthase kinase 3-beta expression in fragile X syndrome model mice. Chen X, Sun W, Pan Y, et al. Neurosciences (Riyadh.) 18(4), 356-62, (2013)

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Optimizations of packed sorbent and inlet temperature for large volume-direct aqueous injection-gas chromatography to determine high boiling volatile organic compounds in water. Yu B, Song Y, Han L, et al. J. Chromatogr. A 1356, 221-9, (2014)

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Voltage changes in the lithium dilution cardiac output sensor after exposure to blood from horses given xylazine. Ambrisko TD and Moens Y Br. J. Anaesth. 112(2), 367-9, (2014)

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Homocysteine inhibits hepatocyte proliferation via endoplasmic reticulum stress. Yu X, Lv J, Zhu Y, et al. PLoS ONE 8(1), e54265, (2013)

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β-catenin directly sequesters adipocytic and insulin sensitizing activities but not osteoblastic activity of PPARγ2 in marrow mesenchymal stem cells. Rahman S, Czernik PJ, Lu Y, et al. PLoS ONE 7(12), e51746, (2012)

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Notch signaling-related therapeutic strategies with novel drugs in neuroblastoma spheroids. Ayla S, Bilir A, Soner BC, et al. J. Pediatr. Hematol. Oncol. 36(1), 37-44, (2014)

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Merck 14,5528

Fieser 1,609 / Fieser 2,246 / Fieser 4,298 / Fieser 5,677 / Fieser 13,332 / Fieser 16,194

Corp MSDS 1 (1), 2152:D / RegBook 1 (3), 3319:D / Sax 6, 1710

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