Cycloisomerization of 1,4-, 1,5-,1,6-, and 1,7-Enynes
The enyne cycloisomerization is one of the most important reaction for the synthesis of functionalized cyclic structures.1 The structural complexity resulting from the cyclization of relatively simpl...
William Sommer
Aldrich ChemFiles 2009, 9.5, 4.
Keywords: Cyclizations, Cycloadditions, Cycloisomerizations, Rautenstrauch rearrangements, Rearrangements, transformation
Intermolecular [4+3]-Annulation
In 2008, Toste and coworkers developed a new method to synthesize azepines using a Au(III) catalyst.1 Following the work done by the group with sulfoxides showing that the allylgold intermediate can ...
William Sommer
Aldrich ChemFiles 2009, 9.5, 4.
Keywords: Cycloadditions
Gold Catalyst in Chemical Synthesis
Introduction Hashmi, Toste, Echavarren, and Haruta, among others, have fueled the advance of gold into the forefront of transition metal catalysis.1,2 Phosphine ligated gold(I) complexes have risen a...
Keywords: Asymmetric synthesis, Building blocks, Catalysis, Claisen rearrangement, Conia-Ene Reaction, Cyclizations, Cycloadditions, Cycloisomerizations, Cyclopropanations, Deprotonations, Ene reaction, Hydroaminations, Hydrogenations, Isomerizations, Ligands, Rautenstrauch rearrangements, Rearrangements, Reductions, Schmidt Reaction, Substitutions