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676713 Aldrich

1,2-Dibromo-3-chloropropane

97%

Synonym: DBCP

  • CAS Number 96-12-8

  • Linear Formula CH2BrCHBrCH2Cl

  • Molecular Weight 236.33

  •  Beilstein Registry Number 1732077

  •  EC Number 202-479-3

  •  MDL number MFCD00039365

  •  PubChem Substance ID 24885325

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Properties

Related Categories Alkyl, Building Blocks, Chemical Synthesis, Halogenated Hydrocarbons, Organic Building Blocks More...
assay   97%
refractive index   n/D 1.5542
bp   60-65 °C/7.5 mmHg
density   2.081 g/mL at 25 °C

Description

Packaging

5, 25 g in glass bottle

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1,2-<WBR>Dibromo-<WBR>3-<WBR>chloropropane

PESTANAL®, analytical standard

200 μg/mL in methanol, analytical standard

5000 μg/mL in methanol, analytical standard

certified reference material

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2872 6.1 / PGIII
WGK Germany 
3
RTECS 
TX8750000
Flash Point(F) 
168.8 °F
Flash Point(C) 
76 °C

Protocols & Articles

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Peer-Reviewed Papers

References

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Utilization of trihalogenated propanes by Agrobacterium radiobacter AD1 through heterologous expression of the haloalkane dehalogenase from Rhodococcus sp. strain M15-3. Bosma T, Kruizinga E, de Bruin EJ, et al. Appl. Environ. Microbiol. 65(10), 4575-81, (1999)

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1,2-Dibromo-3-chloropropane. Rep. Carcinog. 12, 134-5, (2011)

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1,2-Dibromo-3-chloropropane. Rep. Carcinog. 11, III81-2, (2004)

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[Evidence of toxic effect of a chemical on reproduction ignored]. Albin M and Giwercman A Lakartidningen. 106(37), 2296-7, (2009)

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1,2-Dibromo-3-chloropropane. Rep. Carcinog. 10, 79-80, (2002)

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1,2-Dibromo-3-chloropropane. IARC Monogr. Eval. Carcinog. Risks Hum. 71 Pt 2, 479-500, (1999)

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DBCP. Legator MS Int. J. Occup. Environ. Health 5(3), 241, (1999)

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DBCP in global context: the unchecked power of multinational corporations. LaDou J Int. J. Occup. Environ. Health 5(2), 151-3, (1999)

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Exporting DBCP and other banned pesticides: consideration of ethical issues. Lowry LK and Frank AL Int. J. Occup. Environ. Health 5(2), 135-41, (1999)

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The toxicology of 1,2-dibromo-3-chloropropane (DBCP): a brief review. Teitelbaum DT Int. J. Occup. Environ. Health 5(2), 122-6, (1999)

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Genetic toxicology of 1,2-dibromo-3-chloropropane (DBCP). Teramoto S and Shirasu Y Mutat. Res. 221(1), 1-9, (1989)

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Restoration of spermatogenesis in dibromochloropropane (DBCP)-treated rats by hormone suppression. Meistrich ML, Wilson G, Porter KL, et al. Toxicol. Sci. 76(2), 418-26, (2003)

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Wegener's granulomatosis: Possible role of environmental agents in its pathogenesis. Albert D, Clarkin C, Komoroski J, et al. Arthritis Rheum. 51(4), 656-64, (2004)

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Simultaneous bio-reduction of nitrate, perchlorate, selenate, chromate, arsenate, and dibromochloropropane using a hydrogen-based membrane biofilm reactor. Chung J, Rittmann BE, Wright WF, et al. Biodegradation 18(2), 199-209, (2007)

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Dibromochloropropane inhibits spermatogonial development in rats. Meistrich ML, Wilson G, Shuttlesworth GA, et al. Reprod. Toxicol. 17(3), 263-71, (2003)

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Critical evaluation of the cancer risk of dibromochloropropane (DBCP). Clark HA and Snedeker SM J. Environ. Sci. Health. C. Environ. Carcinog. Ecotoxicol. Rev. 23(2), 215-60, (2005)

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Mutation spectrum of 1,2-dibromo-3-chloropropane, an endocrine disruptor, in the lacI transgenic Big Blue Rat2 fibroblast cell line. Ryu JC, Kim YJ, and Chai YG Mutagenesis 17(4), 301-7, (2002)

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An evaluation of the occupational health risks to workers in a hazardous waste incinerator. Bakoğlu M, Karademir A, and Ayberk S J. Occup. Health 46(2), 156-64, (2004)

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Effects of metronidazole, ipronidazole, and dibromochloropropane on rabbit and human sperm motility and fertility. Foote RH Reprod. Toxicol. 16(6), 749-55, (2002)

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Effect of oxygen on the dehalogenation of 1,2-Dibromo-3-chloropropane by cytochrome P450cam (CYP101). Koe GS and Vilker VL Biotechnol. Prog. 21(4), 1119-27, (2005)

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Metal ions and human sperm mannose receptors. Benoff S, Cooper GW, Centola GM, et al. Andrologie 32(4-5), 317-29, (2000)

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Induction of DNA-lesions in freshly isolated rat hepatocytes by different genotoxins and their reduction by lignin given either as a dietary component or in in vitro conditions. Lábaj J, Slamenová D, Lazarová M, et al. Nutr. Cancer 57(2), 209-15, (2007)

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Agricultural "killing fields": the poisoning of Costa Rican banana workers. Sass R Int. J. Health Serv. 30(3), 491-514, (2000)

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Mortality among a cohort of banana plantation workers in Costa Rica. Hofmann J, Guardado J, Keifer M, et al. Int. J. Occup. Environ. Health 12(4), 321-8, (2006)

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Unwelcome exposure. Rogers T Lancet 364(9439), 1025-6, (2004)

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Reproductive toxicology: current and future directions. Hoyer PB Biochem. Pharmacol. 62(12), 1557-64, (2001)

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Paternal exposures: altered sex ratios. Trasler J Teratology 62(2), 77-8, (2000)

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Merck 14,3020

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