310328 Sigma-Aldrich

Propylene carbonate

anhydrous, 99.7%

Synonym: 1,2-Propanediol cyclic carbonate, 4-Methyl-1,3-dioxolan-2-one



Related Categories Alternative Energy, Anhydrous Solvents, Electrolytes, Lithium-Ion Batteries, Materials Science,
grade   anhydrous
vapor pressure   0.13 mmHg ( 20 °C)
  0.98 mmHg ( 50 °C)
assay   99.7%
autoignition temp.   851 °F
expl. lim.   14.3 %
impurities   <0.002% water
  <0.005% water (100 mL pkg)
refractive index   n20/D 1.421(lit.)
bp   240 °C(lit.)
mp   −55 °C(lit.)
density   1.204 g/mL at 25 °C(lit.)



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Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Precautionary statements 
Hazard Codes (Europe) 
Risk Statements (Europe) 
WGK Germany 
Flash Point(F) 
240.8 °F
Flash Point(C) 
116 °C


Certificate of Analysis

Certificate of Origin

Protocols & Articles


Complex Hydrides: A New Category of Solid-state Lithium Fast-ion Conductors

Research and development of solid-state lithium fast-ion conductors is crucial because they can be potentially used as solid electrolytes in all-solid-state batteries, which may solve the safety and ...
Motoaki Matsuo,1 Hiroyuki Oguchi,1,2 Hideki Maekawa,2 Hitoshi Takamura,2Shin-ichi Orimo,1*
Material Matters Volume 5 Article 4
Keywords: Calorimetry, Deposition, Diffraction, Diffusion, Melting, Nuclear magnetic resonance spectroscopy, Raman spectroscopy, Search, Spectra, Spectroscopy, Substitutions, Support, X-Ray diffraction, transformation

Determination of Water Content in Propylene Carbonate Using Karl Fischer Titration

Water determination in hydrocarbons is relatively straightforward. Lower hydrocarbons dissolve in methanol, however, even if the dissolution is incomplete, the water is rapidly extracted and complete...
Keywords: Pharmaceutical, Solvents, Titrations

Peer-Reviewed Papers


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Mussel-inspired polydopamine-treated polyethylene separators for high-power li-ion batteries. Ryou MH, Lee YM, Park JK, et al. Adv. Mater. 23(27), 3066-70, (2011)


Ionic liquid-nanoparticle hybrid electrolytes and their application in secondary lithium-metal batteries. Lu Y, Das SK, Moganty SS, et al. Adv. Mater. 24(32), 4430-5, (2012)


Density functional theory study of the role of anions on the oxidative decomposition reaction of propylene carbonate. Xing L, Borodin O, Smith GD, et al. J. Phys. Chem. A 115(47), 13896-905, (2011)


A chiral solvent effect in asymmetric organocatalysis. North M and Villuendas P Org. Lett. 12(10), 2378-81, (2010)


Biocompatibility evaluation of electrospun aligned poly (propylene carbonate) nanofibrous scaffolds with peripheral nerve tissues and cells in vitro. Wang Y, Zhao Z, Zhao B, et al. Chin. Med. J. 124(15), 2361-6, (2011)


Polymer synthesis: making the gradient. Lee BY and Cyriac A Nature Chemistry 3(7), 505-7, (2011)


[Influence of aligned electrospinning poly (propylene carbonate) on axonal growth of dorsal root ganglion in vitro]. Zhao Z, Wang Y, Peng J, et al. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 25(2), 171-5, (2011)


Models for liquid-liquid partition in the system propylene carbonate-organic solvent and their use for estimating descriptors for organic compounds. Karunasekara T and Poole CF J. Chromatogr. A 1218(6), 809-16, (2011)


Preparation of flexible and elastic poly(trimethylene carbonate) structures by stereolithography. Schüller-Ravoo S, Feijen J, and Grijpma DW Macromol. Biosci. 11(12), 1662-71, (2011)


Heat capacity in the glass transition range modeled on the basis of heterogeneous dynamics. Richert R J. Chem. Phys. 134(14), 144501, (2011)


Robust cycling of Li-O2 batteries through the synergistic effect of blended electrolytes. Kim BG, Lee JN, Lee DJ, et al. ChemSusChem 6(3), 443-8, (2013)


The effect of plasma lipids on the pharmacokinetics of chlorpyrifos and the impact on interpretation of blood biomonitoring data. Lowe ER, Poet TS, Rick DL, et al. Toxicol. Sci. 108(2), 258-72, (2009)


Organic carbonates as stabilizing solvents for transition-metal nanoparticles. Vollmer C, Thomann R, and Janiak C Dalton Trans. 41(32), 9722-7, (2012)


Theoretical insight into oxidative decomposition of propylene carbonate in the lithium ion battery. Xing L, Wang C, Li W, et al. J. Phys. Chem. B 113(15), 5181-7, (2009)


Selective double quantum resolved correlation experiment for the complete separation of entire proton NMR spectra of enantiomers. Hebbar S, Prabhu UR, and Suryaprakash N J. Magn. Reson. 215, 23-6, (2012)


Carbonates: ecofriendly solvents for palladium-catalyzed direct 2-arylation of oxazole derivatives. Roger J, Verrier C, Le Goff R, et al. ChemSusChem 2(10), 951-6, (2009)


Greening pharmaceutical applications of liquid chromatography through using propylene carbonate-ethanol mixtures instead of acetonitrile as organic modifier in the mobile phases. Tache F, Udrescu S, Albu F, et al. J. Pharm. Biomed. Anal. 75, 230-8, (2013)


The reaction of primary aromatic amines with alkylene carbonates for the selective synthesis of bis-N-(2-hydroxy)alkylanilines: the catalytic effect of phosphonium-based ionic liquids. Selva M, Fabris M, Lucchini V, et al. Org. Biomol. Chem. 8(22), 5187-98, (2010)


An optical microscopy study on the phase structure of poly(L-lactide acid)/poly(propylene carbonate) blends. Gao M, Ren Z, Yan S, et al. J. Phys. Chem. B 116(32), 9832-7, (2012)


Influence of coupling bonds on the anti-tumor activity of polymer-pirarubicin conjugates. Mo G, Hu X, Liu S, et al. Eur. J. Pharm. Sci. 46(5), 329-35, (2012)


Visualization of enantiomers using natural abundant (13)C-filtered single and double quantum selective refocusing experiments: Application to small chiral molecules. Nath N, Baishya B, and Suryaprakash N J. Magn. Reson. 200(1), 101-8, (2009)


Correlation between ion diffusional motion and ionic conductivity for different electrolytes based on ionic liquid. Kaur DP, Yamada K, Park JS, et al. J. Phys. Chem. B 113(16), 5381-90, (2009)


Demixing of severely overlapped ¹H NMR resonances and interpretation of anomalous intensity pattern of dipolar coupled A₃ spins in a weakly aligning medium. Nath N and Suryaprakash N J. Magn. Reson. 207(2), 190-6, (2010)


Dielectric spectroscopy and ultrasonic study of propylene carbonate under ultra-high pressures. Kondrin MV, Gromnitskaya EL, Pronin AA, et al. J. Chem. Phys. 137(8), 084502, (2012)


Rh-catalyzed asymmetric hydrogenation of unsaturated lactate precursors in propylene carbonate. Schäffner B, Andrushko V, Holz J, et al. ChemSusChem 1(11), 934-40, (2008)


Beil. 19,V,4,21

Aldrich MSDS 1, 1551:A / Corp MSDS 1 (2), 2965:D / FT-IR 1 (1), 613:A / FT-IR 2 (1), 979:B / FT-NMR 1 (1), 932:C / IR-Spectra (2), 325:F / IR-Spectra (3), 366:A / NMR-Reference 2 (1), 518:A / RegBook 1 (1), 697:D / Sax 6, 642 / Structure Index 1, 105:A:9 / Vapor Phase 3, 635:C

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