L -2,4-Diaminobutyric acid monohydrochloride
≥98.0% (AT), ≥98.0% (TLC)
DOWNLOAD MSDS (PDF)Synonym: DAB
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CAS Number 1482-98-0
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Empirical Formula (Hill Notation) C4H10N2O2 · HCl
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Molecular Weight 154.60
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Beilstein Registry Number 6086583
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MDL number MFCD01632031
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PubChem Substance ID 24851721
Properties
| Related Categories | A - H, Amino Acids, Biochemicals and Reagents, Chemical Biology, Chemical Synthesis, |
| assay | ≥98.0% (AT) |
| ≥98.0% (TLC) | |
| optical activity | [α]20/D +24±2°, c = 1.2% in 6 M HCl |
| mp | ≥220 °C (dec.)(lit.) |
Description
Biochem/physiol Actions
L-2,4-Diaminobutyric acid (DAB) is a substrate of diaminobutyrate-pyruvate transaminase (EC 2.6.1.46), an enzyme involved in an alternative polyamine biosynthesis pathway in bacteria.
L-2,4-Diaminobutyric acid (DAB, DABA), a non-metabolized amino acid, is useful as a selective GABA uptake inhibitor which may have antitumour activity against hepatoma cells.
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