|Related Categories||Amino Acids, Biochemicals and Reagents, Chemical Biology, Chemical Synthesis, Glycine Derivatives,|
Reagent for the irreversible inactivation of γ-cystathionase1,2; affinity labeling reagent for γ-cystathionase and other enzymes3; peptides containing this amino acid can be tritiated to high specific radioactivity4
L-C-Propargylglycine, a specific inhibitor of H(2)S synthase of cystathionine-γ-lyase (CSE), may be used to study the role of H2S in regulation of biological processes.
L-propargylglycine (PAG), an inhibitor of cystathionine γ-lyase (CSE), is useful in studies of hydrogen sulphide synthesis and bioactivity.
Aldrich Chemistry lists over 600 alkyne building blocks, including a wide array of propargyl alcohols, acetylenic boron reagents, and halogenated substrates for cross-coupling. Additionally, many of ...
Keywords: Building blocks, Coupling reactions, Cross couplings
4. A.N. Eberle, A. Zeller Helv. Chim. Acta 68, 1880, (1985)
Inhibition of endogenous hydrogen sulfide synthesis by PAG protects against ethanol-induced gastric damage in the rat. Chávez-Piña AE, Tapia-Alvarez GR, Navarrete A. Eur. J. Pharmacol. 630, 131-136, (2010)
MicroRNA-21 represses human cystathionine gamma-lyase expression by targeting at specificity protein-1 in smooth muscle cells. Yang G, Pei Y, Cao Q, Wang R. J. Cell Physiol. 227(9), 3192-200, (2011)
Inducible hydrogen sulfide synthesis in chondrocytes and mesenchymal progenitor cells: is h(2) S a novel cytoprotective mediator in the inflamed joint? Fox B, Schantz JT, Haigh R, et al. J. Cell. Mol. Med. 16(4), 896-910, (2012)
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