|Related Categories||AN-AZ, Antibiotics, Antibiotics A to Z, Antibiotics A-F, Antibiotics by Application,|
|optical activity||[α]27/D +12°, c = 1 in methanol(lit.)|
|solubility||ethanol: soluble1 mg/mL (stable at least a week at 4°C.)|
|DMSO: soluble10 mg/mL (stable at least six weeks at −20°C.)|
|methanol: soluble10 mg/mL|
|Gene Information||human ... POLA1(5422), POLD1(5424), POLG(5428)|
Aphidicolin is an antibiotic, a potent antiviral and antimitotic agent and DNA polymerase inhibitor.
Estimated shelf-life is two years. For optimal stability, it should be protected from light and stored desiccated.
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Certificate of Origin
Augmentation by aphidicolin of 1-β-D-arabinofuranosylcytosine-induced c-jun and NF-kappa B activation in a human myeloid leukemia cell line: correlation with apoptosis. Kuwakado, K., et al. Leuk. Res. 19, 645, (1995)
How common are common fragile sites: variation of aphidicolin-induced chromosomal fragile sites in a population of the deer mouse (Peromyscus maniculatus). McAllister, B.F., and Greenbaum, I.F. Hum. Genet. 100, 182-188, (1997)
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