Synonym: Apo A-II
MDL number MFCD00132612
Popular Documents: Datasheet (PDF) | Specification Sheet (PDF)
| Related Categories | Apolipoproteins, Application Index, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, |
| assay | ≥95% (SDS-PAGE) |
| form | buffered aqueous solution |
| mol wt | mol wt 17.38 kDa |
| shipped in | dry ice |
| storage temp. | −20°C |
| Gene Information | human ... APOA2(336) |
Apo A-II constitutes ~20% of the protein moiety of high density lipoprotein (HDL).
Unlike Apo A-I, Apo A-II possesses no activating properties for lectin-cholesterol acyltransferase (LCAT). Furthermore, it was found that Apo A-II inhibits the activation of LCAT by Apo A-I.
Forms dimers in aqueous solutions with an association constant of 5 × 104 M-1. The association is accompanied by an enhancement of ~35% in α-helical content.
Solution in 10 mM ammonium bicarbonate.
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≥85% (SDS-PAGE), buffered aqueous solution
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