|Related Categories||Apolipoproteins, Application Index, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience,|
|form||buffered aqueous solution|
|mol wt||mol wt 17.38 kDa|
|shipped in||dry ice|
|Gene Information||human ... APOA2(336)|
Apo A-II constitutes ~20% of the protein moiety of high density lipoprotein (HDL).
Unlike Apo A-I, Apo A-II possesses no activating properties for lectin-cholesterol acyltransferase (LCAT). Furthermore, it was found that Apo A-II inhibits the activation of LCAT by Apo A-I.
Forms dimers in aqueous solutions with an association constant of 5 × 104 M-1. The association is accompanied by an enhancement of ~35% in α-helical content.
Solution in 10 mM ammonium bicarbonate.
Since cholesterol is a water-insoluble molecule it must be packaged for transport within the plasma. The particles that package cholesterol, cholesteryl esters, and triglycerides for transport, are c...
BioFiles 2007, 2.7, 13.
Keywords: Esterifications, Ligands
Despite their complexity, blood and plasma are abundant biological resources for the discovery of drug targets and biomarkers for human disease. It is estimated that plasma may contain as many as 40,...
BioFiles 2006, 1.5, 2.
Keywords: Gas chromatography
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