Synonym: Rp-Cyclic 3′,5′-hydrogen phosphorothioate adenosine triethylammonium salt, Rp-cAMPS triethylammonium salt
|Related Categories||A-AM, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism,|
|color||white to beige|
|solubility||H2O: soluble10 mg/mL|
|UV absorption||λmax 258 nm|
Rp-Diastereomer of adenosine-3′,5′-cyclic monophosphothioate. Specific membrane-permeable inhibitor of activation by cAMP of cAMP-dependent protein kinase I and II; resistant toward cyclic nucleotide phosphodiesterases; blocks cAMP-mediated effects in numerous systems.
Extremely hygroscopic. Store desiccated.
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Identification Of The Structural Determinant Responsible For The Phosphorylation Of G-protein Activated Potassium Channel 1 By CAMP-dependent Protein Kinase. Müllner, C., et al. FASEB J. 276, 6218-26, (2009)
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