A1973 Sigma

Axl/Fc Chimera human

≥90% (SDS-PAGE), recombinant, expressed in NSO cells

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Properties

Related Categories Application Index, Biochemicals and Reagents, Cancer Research, Cell Biology, Cell Signaling Enzymes,
recombinant   expressed in NSO cells
assay   ≥90% (SDS-PAGE)
mol wt   calculated mol wt 73.8 kDa
  mol wt 100-110 kDa by SDS-PAGE (reducing)
storage temp.   −20°C
Gene Information   human ... AXL(558)

Description

Analysis Note

Measured by its ability to bind recombinant human Gas6.

Biochem/physiol Actions

Member of a tyrosine kinase receptor subfamily shown to be involved in hematopoiesis, embryonic development, tumorigenesis, and testicular function regulation.

General description

Extracellular domain of human Axl (residues 1-442) fused to C-terminal histidine-tagged Fc region of human IgG1.

Physical form

Lyophilized from a 0.2 μm filtered solution of phosphate buffered saline.

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