Synonym: Trasylol, Trypsin inhibitor (basic)
|Related Categories||AN-AZ, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Culture,|
|mol wt||mol wt ~6,500|
|suitability||suitable for cell culture|
|Gene Information||cow ... PTI(404172)|
Another commonly used unit of activity is the KIU (Kallikrein Inhibitor Unit).
1 TIU ∼ 1,300 KIU.
Note: When benzoyl-
Aprotinin is a protein consisting of 58 amino acids, arranged in a single polypeptide chain that is crosslinked by three disulfide bridges.
One trypsin inhibitor unit (TIU) will decrease the activity of 2 trypsin units by 50% where one trypsin unit will hydrolyze 1.0 μmole of Nα-benzoyl-
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recombinant, expressed in Nicotiana, ≥5 TIU/mg protein, ≥98% (SDS-PAGE)
lyophilized, ~80% (HPCE), crystalline (fine), white, ≥3500 U/mg
saline solution, 3-7 TIU/mg protein
lyophilized powder, 3-8 TIU/mg solid
lyophilized powder, 3-7 TIU/mg solid
Certificate of Analysis
Certificate of Origin
2. SCOPE The scope of this procedure is all products that have a specification for Aprotinin activity.
Keywords: Enzymology, Extinction coefficient
Trautschold, I., et al. Biochem. Pharmacol. 16, 59, (1967)
Review: Biochemistry of aprotinin and aprotinin-like inhibitors. Gebhard, W. Res. Monogr. Cell Tissue Physiol. 12, 375, (1986)
Beynon, R.J. and Bond, J.S., ed. Proteolytic Enzymes: A Practical Approach, (1989), 247
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