B3061 Sigma

Borrelidin

from Streptomyces parvulus, ≥98% (HPLC)

DOWNLOAD MSDS (PDF)

Synonym: 2-(7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl)-cyclopentanecarboxylic acid, Borrelidine, Cyclopentanecarboxylic acid, NSC 216128, Treponemycin

Properties

Related Categories A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics A-F,
biological source   from Streptomyces parvulus
assay   ≥98% (HPLC)
solubility   DMSO: soluble1 mg/mL
  methanol: soluble1 mg/mL
shipped in   wet ice
storage temp.   −20°C

Description

Biochem/physiol Actions

Borrelidin is a potent angiogenesis inhibitor that induces apoptosis in capillary tube-forming cells. Also displays antimalarial activity against drug-resistant Plasmodia. Antimicrobial and selective threonyl t-RNA synthetase inhibitor.

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Borrelidin

from Streptomyces sp., ≥95% (HPLC), lyophilized powder

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