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B8810 Sigma

BAY 41-2272

≥97% (HPLC), powder

DOWNLOAD MSDS (PDF)

Synonym: 3-(4-Amino-5-cyclopropylpyrimidin-2-yl)-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine

  • Empirical Formula (Hill Notation) C20H17FN6

  • Molecular Weight 360.39

  •  MDL number MFCD06411391

  •  PubChem Substance ID 24892096

BAY 41-2272 ≥97% (HPLC), powder
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Properties

Related Categories Approved Therapeutics/Drug Candidates, B, Bayer, Bioactive Small Molecules, Cell Biology,
assay   ≥97% (HPLC)
form   powder
color   white
mp   210.5-211.4 °C
solubility   DMSO: soluble26 mg/mL at 60 °C
storage temp.   2-8°C

Description

Biochem/physiol Actions

BAY 41-2272 is an activator of soluble guanylate cyclase at a novel, NO-independent regulatory site. BAY 41-2272 is the first product that stimulates sGC through a non-NO mechanism. BAY 41-2272 inhibits platelet aggregation and induces vasorelaxation without nitrate tolerance.

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