|Related Categories||Antibiotics, Antibiotics A to Z, Antibiotics A-F, Antifungal, Bioactive Small Molecules,|
|biological source||from Cordyceps militaris|
|Gene Information||rat ... Adora1(29290)|
Cordycepin is an adenosine analogue that is readily converted to cordycepin 5′-triphosphate; can be used for 3′-end labeling of RNA.
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P261-P301 + P310-P305 + P351 + P338|
|Personal Protective Equipment||Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||T|
|Risk Statements (Europe)||25-36/37/38|
|Safety Statements (Europe)||26-45|
|RIDADR||UN 2811 6.1 / PGIII|
Cordycepin (3'-deoxyadenosine) pentostatin (deoxycoformycin) combination treatment of mice experimentally infected with Trypanosoma evansi. Dalla Rosa L, da Silva AS, Gressler LT, et al. Parasitology 140(5), 663-71, (2013)
Cordycepin suppresses TNF-α-induced NF-κB activation by reducing p65 transcriptional activity, inhibiting IκBα phosphorylation, and blocking IKKγ ubiquitination. Ren Z, Cui J, Huo Z, et al. Int. Immunopharmacol. 14(4), 698-703, (2012)
Cordycepin as a sensitizer to tumour necrosis factor (TNF)-α-induced apoptosis through eukaryotic translation initiation factor 2α (eIF2α)- and mammalian target of rapamycin complex 1 (mTORC1)-mediated inhibition of nuclear factor (NF)-κB. Kadomatsu M, Nakajima S, Kato H, et al. Clin. Exp. Immunol. 168(3), 325-32, (2012)
Optimization of solid state culture conditions for the production of adenosine, cordycepin, and D-mannitol in fruiting bodies of medicinal caterpillar fungus Cordyceps militaris (L.:Fr.) Link (Ascomycetes). Lim L, Lee C, and Chang E Int. J. Med. Mushrooms 14(2), 181-7, (2012)
Cultivation of medicinal caterpillar fungus, Cordyceps militaris (Ascomycetes), and production of cordycepin using the spent medium from levan fermentation. Wu FC, Chen YL, Chang SM, et al. Int. J. Med. Mushrooms 15(4), 393-405, (2013)
Apoptosis induction of human prostate carcinoma cells by cordycepin through reactive oxygen species‑mediated mitochondrial death pathway. Lee HH, Park C, Jeong JW, et al. Int. J. Oncol. 42(3), 1036-44, (2013)
Triacetyl-3-hydroxyphenyladenosine, a derivative of cordycepin, attenuates atherosclerosis in apolipoprotein E-knockout mice. Zhao Z, Song G, Tian H, et al. Exp. Biol. Med. (Maywood.) 237(11), 1262-72, (2012)
Ethanol extracts of fruiting bodies of Antrodia cinnamomea exhibit anti-migration action in human adenocarcinoma CL1-0 cells through the MAPK and PI3K/AKT signaling pathways. Chen YY, Chou PY, Chien YC, et al. Phytomedicine 19(8-9), 768-78, (2012)
Ras/ERK1 pathway regulation of p27KIP1-mediated G1-phase cell-cycle arrest in cordycepin-induced inhibition of the proliferation of vascular smooth muscle cells. Jung SM, Park SS, Kim WJ, et al. Eur. J. Pharmacol. 681(1-3), 15-22, (2012)
High-resolution structures of complexes of plant S-adenosyl-L-homocysteine hydrolase (Lupinus luteus). Brzezinski K, Dauter Z, and Jaskolski M Acta Crystallogr. D, Biol. Crystallogr. 68(Pt 3), 218-31, (2012)
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