Synonym: Phomin
CAS Number 14930-96-2
Empirical Formula (Hill Notation) C29H37NO5
Molecular Weight 479.61
Beilstein Registry Number 1096207
EC Number 239-000-2
MDL number MFCD00077704
PubChem Substance ID 24892890
Popular Documents: Product Information Sheet (PDF) | Specification Sheet (PDF)
| Related Categories | Actin Inhibitors and Probes, Antibiotics, Antibiotics A to Z, Antibiotics A-F, Antibiotics by Application, |
| Quality Level | PREMIUM |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white |
| solubility | DMSO: soluble10 mg/mL |
| storage temp. | −20°C |
One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin,1 and in studies on cytokinesis.2 Probe for the two hexose-transport systems in rat L6 myoblasts.3
Cell permeable fungal toxin that disrupts contractile microfilaments by inhibiting actin polymerization. This, in turn, induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.
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