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CKOZFN14684 Sigma

CompoZr® Knockout ZFN Kit

Human MTA1 (NM_004689)

Properties

Related Categories CompoZr Knockout ZFN Kits, Functional Genomics and RNAi, Human CompoZr Knockout ZFN Kits, MK-MX, Molecular Biology More...
NCBI accession no.   NM_004689
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... MTA1(9112)

Description

General description

CompoZr Knockout ZFNs create targeted double strand breaks at a gene specific target locus. Through the cellular process of Non-Homologous End Joining, this double strand break can result in modification of the DNA sequence and therefore create a functional knockout of the targeted gene. To provide the best chance of creating a functional gene knockout, CompoZr Knockout ZFNs are targeted to the first 2/3 of the coding region for the gene of interest.

Legal Information

All Zinc Finger Nucleases are sold under license from Sangamo Biosciences. For a copy of the Label License provided with purchase of CompoZr ZFNs, please visit the ZFN Label License page.

CompoZr is a registered trademark of Sigma-Aldrich Co. LLC

Physical form

CompoZr Knockout ZFNs are provided as 10 aliquots of mRNA encoding for the ZFNs along with plasmid DNA for both ZFN pairs. Also included in the kit are custom-designed primers, that allow for determination of the rate of mutation and for screening of individual clones that have the desired mutational event, and positive control DNA that has been modified using the CompoZr Knockout ZFN.

Price and Availability

Technical Service:

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