Synonym: Digoxin-BSA
MDL number MFCD01323187
| Related Categories | Albumin, Biochemicals and Reagents, Modified Albumins, Proteins and Derivatives |
| form | lyophilized powder |
| extent of labeling | ~10 mol Digoxin per mol albumin |
| storage temp. | 2-8°C |
| Gene Information | cow ... ALB(280717) |
Antigen-protein conjugate.
Lyophilized from 0.06 M Tris
Digoxin-BSA bovine is a cardioactive glycoside which can increase intracellular calcium concentration through Na+/K+-ATPase pump inhibition. Digoxin has been used in treatments of heart related disease and also studies of cancer treatments. It has shown the ability to inhibit prostate cancer cell growth, but has also shown a reduction in the efficiency of chemotherapy (reduced drug absorption) by increasing the amount of P-glycoprotein (Pgp).
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