D7692 Sigma

Diethylumbelliferyl phosphate

≥98% (HPLC), oil

DOWNLOAD MSDS (PDF)

Synonym: DEUP, UBP

  • CAS Number 897-83-6

  • Empirical Formula (Hill Notation) C14H17O6P

  • Molecular Weight 312.25

  •  PubChem Substance ID 24894155

Properties

Related Categories A to C, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cholesterol esterase,
assay   ≥98% (HPLC)
form   oil
color   colorless to yellow
solubility   DMSO: >5 mg/mL
storage temp.   −20°C

Description

Biochem/physiol Actions

Diethylumbelliferyl phosphate is a selective, potent cholesterol esterase inhibitor. It blocks steroidogenesis primarily by preventing cholesterol transport into the mitochondria of steroidogenic cells. Inhibitors of cholesterol esterase are anticipated to limit the absorption of dietary cholesterol. IC50 = 11.6 μM.

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